The advent of single-cell RNA sequencing (scRNA-seq) has provided insight into the tumour
immune microenvironment (TIME). This review focuses on the application of scRNA-seq in …

Tumor-associated macrophages (TAMs) are important immune cells in the tumor
microenvironment, and their invasion in tumors is closely related to poor prognosis …

CD68 plays a critical role in promoting phagocytosis; however, the function of CD68 in tumor
immunity and prognosis remains unknown. We analyzed CD68 expression among 33 tumor …

Background Gliomas are one of the most common types of primary tumors in central nervous
system. Previous studies have found that macrophages actively participate in tumor growth …

The glioma tumor microenvironment (TME), composed of several noncancerous cells and
biomolecules is known for its complexity of cancer-immune system interaction. Given that …

Gliomas are primary malignant brain tumors. Monocytes have been proved to actively
participate in tumor growth. Weighted gene co-expression network analysis was used to …

Tumor-infiltrating immune cells (TIICs) have become an important source of markers for
predicting the clinical outcomes of cancer patients. However, measurements of cellular …

Purpose Glioblastoma (GBM) is the most common and deadly brain tumor. We aimed to
reveal potential prognostic GBM marker genes, elaborate their functions, and build an …

Existing therapeutic strategies for gliomas are restricted; hence, exploration for novel
diagnostic indicator and treatment is essential. Here, we performed bioinformatic analyses …

Simple Summary Immunotherapy targeting immune checkpoints and stromal cells in the
tumor microenvironment is currently one of the most promising directions for tumor therapy …