The hyperfocusing hypothesis: a new account of cognitive dysfunction in schizophrenia

SJ Luck, B Hahn, CJ Leonard, JM Gold - Schizophrenia bulletin, 2019 - academic.oup.com
Impairments in basic cognitive processes such as attention and working memory are
commonly observed in people with schizophrenia and are predictive of long-term outcome …

Neuronal and brain morphological changes in animal models of schizophrenia

G Flores, JC Morales-Medina, A Diaz - Behavioural brain research, 2016 - Elsevier
Schizophrenia, a severe and debilitating disorder with a high social burden, affects 1% of
the adult world population. Available therapies are unable to treat all the symptoms, and …

Working memory impairment across psychotic disorders

JM Gold, DM Barch, LM Feuerstahler… - Schizophrenia …, 2019 - academic.oup.com
Background Working memory (WM) has been a central focus of cognitive neuroscience
research because WM is a resource that is involved in many different cognitive operations …

Posterior parietal cortex dysfunction is central to working memory storage and broad cognitive deficits in schizophrenia

B Hahn, BM Robinson, CJ Leonard, SJ Luck… - Journal of …, 2018 - jneurosci.org
PFC dysfunction is widely believed to underlie working memory (WM) deficits in people with
schizophrenia (PSZ), but few studies have focused on measures of WM storage devoid of …

Is attentional filtering impaired in schizophrenia?

SJ Luck, CJ Leonard, B Hahn, JM Gold - Schizophrenia bulletin, 2019 - academic.oup.com
Recent evidence suggests that schizophrenia involves hyperfocusing, an unusually narrow
but intense focusing of processing resources. This appears to contradict the classic idea that …

Working memory in people with schizophrenia

JM Gold, SJ Luck - … Functioning in Schizophrenia: Leveraging the RDoC …, 2022 - Springer
Working memory (WM) refers to the ability to maintain a small number of representations in
an activated, easily accessible state for a short period of time in the service of ongoing …

Impaired suppression of delay-period alpha and beta is associated with impaired working memory in schizophrenia

MA Erickson, MA Albrecht, B Robinson, SJ Luck… - Biological Psychiatry …, 2017 - Elsevier
Background Although patients with schizophrenia (PSZ) frequently exhibit reduced working
memory capacity relative to healthy control subjects (HCS), the mechanisms that underlie …

Hyperfocusing of attention on goal-related information in schizophrenia: Evidence from electrophysiology.

R Sawaki, J Kreither, CJ Leonard… - Journal of abnormal …, 2017 - psycnet.apa.org
Schizophrenia clearly involves impairments of attention, but the precise nature of these
impairments has been difficult to determine. One possibility is that the deficit in attention is a …

Abnormal cortical neural synchrony during working memory in schizophrenia

SS Kang, AW MacDonald III, MV Chafee, CH Im… - Clinical …, 2018 - Elsevier
Objective To better understand the origins of working memory (WM) impairment in
schizophrenia we investigated cortical oscillatory activity in people with schizophrenia (PSZ) …

Abnormalities in Attention and Working Memory in Schizophrenia: The Hyperfocusing Hypothesis

JM Gold, SJ Luck - Current Directions in Psychological …, 2024 - journals.sagepub.com
People with schizophrenia suffer from hallucinations and delusions as well as from
significant cognitive impairments. Working memory is a critical resource for many complex …