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The hyperfocusing hypothesis: a new account of cognitive dysfunction in schizophrenia
Impairments in basic cognitive processes such as attention and working memory are
commonly observed in people with schizophrenia and are predictive of long-term outcome …
commonly observed in people with schizophrenia and are predictive of long-term outcome …
Neuronal and brain morphological changes in animal models of schizophrenia
G Flores, JC Morales-Medina, A Diaz - Behavioural brain research, 2016 - Elsevier
Schizophrenia, a severe and debilitating disorder with a high social burden, affects 1% of
the adult world population. Available therapies are unable to treat all the symptoms, and …
the adult world population. Available therapies are unable to treat all the symptoms, and …
Working memory impairment across psychotic disorders
Background Working memory (WM) has been a central focus of cognitive neuroscience
research because WM is a resource that is involved in many different cognitive operations …
research because WM is a resource that is involved in many different cognitive operations …
Posterior parietal cortex dysfunction is central to working memory storage and broad cognitive deficits in schizophrenia
PFC dysfunction is widely believed to underlie working memory (WM) deficits in people with
schizophrenia (PSZ), but few studies have focused on measures of WM storage devoid of …
schizophrenia (PSZ), but few studies have focused on measures of WM storage devoid of …
Is attentional filtering impaired in schizophrenia?
Recent evidence suggests that schizophrenia involves hyperfocusing, an unusually narrow
but intense focusing of processing resources. This appears to contradict the classic idea that …
but intense focusing of processing resources. This appears to contradict the classic idea that …
Working memory in people with schizophrenia
Working memory (WM) refers to the ability to maintain a small number of representations in
an activated, easily accessible state for a short period of time in the service of ongoing …
an activated, easily accessible state for a short period of time in the service of ongoing …
Impaired suppression of delay-period alpha and beta is associated with impaired working memory in schizophrenia
Background Although patients with schizophrenia (PSZ) frequently exhibit reduced working
memory capacity relative to healthy control subjects (HCS), the mechanisms that underlie …
memory capacity relative to healthy control subjects (HCS), the mechanisms that underlie …
Hyperfocusing of attention on goal-related information in schizophrenia: Evidence from electrophysiology.
Schizophrenia clearly involves impairments of attention, but the precise nature of these
impairments has been difficult to determine. One possibility is that the deficit in attention is a …
impairments has been difficult to determine. One possibility is that the deficit in attention is a …
Abnormal cortical neural synchrony during working memory in schizophrenia
Objective To better understand the origins of working memory (WM) impairment in
schizophrenia we investigated cortical oscillatory activity in people with schizophrenia (PSZ) …
schizophrenia we investigated cortical oscillatory activity in people with schizophrenia (PSZ) …
Abnormalities in Attention and Working Memory in Schizophrenia: The Hyperfocusing Hypothesis
People with schizophrenia suffer from hallucinations and delusions as well as from
significant cognitive impairments. Working memory is a critical resource for many complex …
significant cognitive impairments. Working memory is a critical resource for many complex …