COVID-19 annual update: a narrative review

M Biancolella, VL Colona, L Luzzatto, JL Watt… - Human genomics, 2023‏ - Springer
Three and a half years after the pandemic outbreak, now that WHO has formally declared
that the emergency is over, COVID-19 is still a significant global issue. Here, we focus on …

COVID-19 is a coronary artery disease risk equivalent and exhibits a genetic interaction with ABO blood type

JR Hilser, NJ Spencer, K Afshari… - … and Vascular Biology, 2024‏ - ahajournals.org
BACKGROUND: COVID-19 is associated with acute risk of major adverse cardiac events
(MACE), including myocardial infarction, stroke, and mortality (all-cause). However, the …

[HTML][HTML] The Interplay between Airway Cilia and Coronavirus Infection, Implications for Prevention and Control of Airway Viral Infections

X Dai, R Xu, N Li - Cells, 2024‏ - mdpi.com
Coronaviruses (CoVs) are a class of respiratory viruses with the potential to cause severe
respiratory diseases by infecting cells of the upper respiratory tract, bronchial epithelium …

[HTML][HTML] Long COVID facts and findings: a large-scale online survey in 74,075 Chinese participants

S Qin, Y Zhang, Y Li, L Huang, T Yang, J Si… - The Lancet Regional …, 2024‏ - thelancet.com
Background Research on long COVID in China is limited, particularly in terms of large-
sample epidemiological data and the effects of recent SARS-CoV-2 sub-variants. China …

Estimating the heritability of SARS-CoV-2 susceptibility and COVID-19 severity

KLR Brown, V Ramlall, M Zietz, U Gisladottir… - Nature …, 2024‏ - nature.com
SARS-CoV-2 has infected over 340 million people, prompting therapeutic research. While
genetic studies can highlight potential drug targets, understanding the heritability of SARS …

Complex patterns of multimorbidity associated with severe COVID-19 and long COVID

M Pietzner, S Denaxas, S Yasmeen, MA Ulmer… - Communications …, 2024‏ - nature.com
Background Early evidence that patients with (multiple) pre-existing diseases are at highest
risk for severe COVID-19 has been instrumental in the pandemic to allocate critical care …

Three-year outcomes of post-acute sequelae of COVID-19

M Cai, Y **e, EJ Topol, Z Al-Aly - Nature medicine, 2024‏ - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes post-
acute sequelae of coronavirus disease 2019 (COVID-19)(PASC) in many organ systems …

Stratified analyses refine association between TLR7 rare variants and severe COVID-19

J Boos, CI van der Made, G Ramakrishnan… - Human Genetics and …, 2024‏ - cell.com
Despite extensive global research into genetic predisposition for severe COVID-19,
knowledge on the role of rare host genetic variants and their relation to other risk factors …

Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection

A Marchal, ET Cirulli, I Neveux, E Bellos… - Human Genetics and …, 2024‏ - cell.com
Human genetic studies of critical COVID-19 pneumonia have revealed the essential role of
type I interferon-dependent innate immunity to SARS-CoV-2 infection. Conversely, an …

Environmental variation and genetic diversity contribute to population differences in immune responses to SARS-CoV-2 and COVID-19 risk

M Rotival, L Quintana-Murci - Genes & Immunity, 2024‏ - nature.com
The COVID-19 pandemic has brought to light considerable clinical variation among
individuals infected with SARS-CoV-2, ranging from asymptomatic cases to fatal outcome …