Novel syntheses of azetidines and azetidinones

A Brandi, S Cicchi, FM Cordero - Chemical Reviews, 2008 - ACS Publications
Four-membered monocyclic aza-heterocycles, 1 despite their indisputable importance as
bioactive compounds and pharmaceutical tools, have received by the chemical community …

Stereoselective synthesis of β-lactams: recent examples

A Saura-Sanmartin, L Andreu-Ardil - Organic & Biomolecular …, 2023 - pubs.rsc.org
The synthesis of β-lactam derivatives is a research topic of great interest due to the
biological activity of these molecules. Indeed, there are several antibiotics which include a β …

Comprehensive survey of combinatorial library synthesis: 2005

RE Dolle, B Le Bourdonnec, GA Morales… - Journal of …, 2006 - ACS Publications
Comprehensive Survey of Combinatorial Library Synthesis: 2005 | ACS Combinatorial Science
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An update on the synthesis of β-lactams

MT Aranda, P Perez-Faginas… - Current Organic …, 2009 - ingentaconnect.com
Because the renewed interest of β-lactams in organic and medicinal chemistry, research in
this field continues in producing new appealing progresses. This review tries to call the …

Novel and recent synthesis and applications of β-lactams

L Troisi, C Granito, E Pindinelli - Heterocyclic Scaffolds I: ß-Lactams, 2010 - Springer
In this chapter, a comprehensive overview of the most significant and interesting
contributions published from 2000 until now, concerning the preparation of novel β-lactam …

Spirocyclic β-lactams: synthesis and biological evaluation of novel heterocycles

SS Bari, A Bhalla - Heterocyclic Scaffolds I: ß-Lactams, 2010 - Springer
Abstract β-Lactam rings containing compounds are a group of antibiotics of unparalleled
importance in chemotherapy. Considerable effort has been reported in the development of …

Parallel synthesis of homochiral β-amino acids

SG Davies, AW Mulvaney, AJ Russell, AD Smith - Tetrahedron: Asymmetry, 2007 - Elsevier
The parallel asymmetric synthesis of an array of 30 β-amino acids of high enantiomeric
purity using the conjugate addition of homochiral lithium N-benzyl-N-(α-methylbenzyl) amide …

Synthetic access to optically active isoflavans by using allylic substitution

Y Takashima, Y Kaneko, Y Kobayashi - Tetrahedron, 2010 - Elsevier
A general approach to the (S)-and (R)-isoflavans was invented, and efficiency of the method
was demonstrated by the synthesis of (S)-equol ((S)-3),(R)-sativan ((R)-4), and (R)-vestitol …

Synthesis of 3-(aryl) alkenyl-β-lactams by an efficient application of olefin cross-metathesis on solid support

SA Testero, EG Mata - Organic Letters, 2006 - ACS Publications
An efficient cross-metathesis on solid support for the synthesis of β-lactam analogues of
cholesterol absorption inhibitors is described. The applied strategy allows the introduction of …

Polymer-Supported Syntheses of Heterocycles Bearing Oxazine and Thiazine Scaffolds

P Králová, V Ručilová, M Soural - ACS combinatorial science, 2018 - ACS Publications
In this review, we summarize synthetic approaches to preparing single or fused oxazine and
thiazine derivatives using solid-phase synthesis (SPS). The literature survey revealed that …