Protein tyrosine phosphatase receptor gamma (PTPRG) is known to interact with and
regulate several tyrosine kinases, exerting a tumor suppressor role in several type of …

Members of the Protein Tyrosine Phosphatase (PTPs) family are associated with growth
regulation and cancer development. Acting as natural counterpart of tyrosine kinases (TKs) …

Chronic myelogenous leukemia (CML) is the most common myeloproliferative disease.
Protein tyrosine phosphatase receptor type γ (PTPRG) is a tumor suppressor gene and a …

Many epithelia secrete bicarbonate-rich fluid to generate flow, alter viscosity, control pH and
potentially protect luminal and intracellular structures from chemical stress. Bicarbonate is a …

Protein tyrosine phosphatases (PTPs), of the receptor and non-receptor classes, are key
signaling molecules that play critical roles in cellular regulation underlying diverse …

Solid tumors, including breast carcinomas, are heterogeneous but typically characterized by
elevated cellular turnover and metabolism, diffusion limitations based on the complex tumor …

Background: Protein phosphorylation is one of the essential steps in cell signaling, and
aberrant phosphorylation is a common event in human cancer. The expression of receptor …

Simple Summary The chromosomal alteration t (9; 22) generating the BCR-ABL1 fusion
protein represents the principal feature that distinguishes some types of leukemia. An …

Background Protein tyrosine phosphatase receptor gamma (PTPRG) is a ubiquitously
expressed member of the protein tyrosine phosphatase family known to act as a tumor …

Asplenic individuals are compromised not only in their ability to destroy infectious agents,
but are at increased risk for death from autoimmune disease, certain tumors, and ischemic …