Influence of the mechanical properties of biomaterials on degradability, cell behaviors and signaling pathways: current progress and challenges
L Wang, C Wang, S Wu, Y Fan, X Li - Biomaterials science, 2020 - pubs.rsc.org
The development of suitable biomaterials with the ability to improve repair and regeneration
of human tissues is continuously in progress, and mechanical properties of biomaterials play …
of human tissues is continuously in progress, and mechanical properties of biomaterials play …
Design, materials, and mechanobiology of biodegradable scaffolds for bone tissue engineering
A review about design, manufacture, and mechanobiology of biodegradable scaffolds for
bone tissue engineering is given. First, fundamental aspects about bone tissue engineering …
bone tissue engineering is given. First, fundamental aspects about bone tissue engineering …
Osteocytes: master orchestrators of bone
Osteocytes comprise the overwhelming majority of cells in bone and are its only true
“permanent” resident cell population. In recent years, conceptual and technological …
“permanent” resident cell population. In recent years, conceptual and technological …
Aging and bone
AL Boskey, R Coleman - Journal of dental research, 2010 - journals.sagepub.com
Bones provide mechanical and protective function, while also serving as housing for marrow
and a site for regulation of calcium ion homeostasis. The properties of bones do not remain …
and a site for regulation of calcium ion homeostasis. The properties of bones do not remain …
Cell-fate decision of mesenchymal stem cells toward osteocyte differentiation is committed by spheroid culture
Osteocytes are mechanosensory commander cells to regulate bone remodeling throughout
the lifespan. While the osteocytes are known as terminally differentiated cells derived from …
the lifespan. While the osteocytes are known as terminally differentiated cells derived from …
Osteocyte calcium signals encode strain magnitude and loading frequency in vivo
Osteocytes are considered to be the major mechanosensory cells of bone, but how
osteocytes in vivo process, perceive, and respond to mechanical loading remains poorly …
osteocytes in vivo process, perceive, and respond to mechanical loading remains poorly …
Osteocytes and primary cilia
Abstract Purpose of Review The purpose of this review is to provide a background on
osteocytes and the primary cilium, discussing the role it plays in osteocyte mechanosensing …
osteocytes and the primary cilium, discussing the role it plays in osteocyte mechanosensing …
[HTML][HTML] In situ intracellular calcium oscillations in osteocytes in intact mouse long bones under dynamic mechanical loading
Osteocytes have been hypothesized to be the major mechanosensors in bone. How in situ
osteocytes respond to mechanical stimuli is still unclear because of technical difficulties. In …
osteocytes respond to mechanical stimuli is still unclear because of technical difficulties. In …
Using confocal imaging approaches to understand the structure and function of osteocytes and the lacunocanalicular network
Although overlooked in the past, osteocytes have come to the forefront of skeletal biology
and are now recognized as a key cell type that integrates hormonal, mechanical and other …
and are now recognized as a key cell type that integrates hormonal, mechanical and other …
Osteocyte-mediated translation of mechanical stimuli to cellular signaling and its role in bone and non-bone-related clinical complications
Y Yan, L Wang, L Ge, JL Pathak - Current osteoporosis reports, 2020 - Springer
Abstract Purpose of Review Osteocytes comprise> 95% of the cellular component in bone
tissue and produce a wide range of cytokines and cellular signaling molecules in response …
tissue and produce a wide range of cytokines and cellular signaling molecules in response …