DNA replication: Mechanisms and therapeutic interventions for diseases

HY Song, R Shen, H Mahasin, YN Guo, DG Wang - MedComm, 2023 - Wiley Online Library
Accurate and integral cellular DNA replication is modulated by multiple replication‐
associated proteins, which is fundamental to preserve genome stability. Furthermore …

Expression, potential biological behaviour and clinical significance of MCM3 in pancreatic adenocarcinoma: a comprehensive study integrating high throughput …

Y Chen, LY Li, JD Li, RQ He, ZG Huang… - Annals of …, 2024 - Taylor & Francis
Background Minichromosome maintenance complex component 3 (MCM3) plays a key role
in various tumours. However, it remains largely unknown what the specific role and clinical …

Sequence specificity of an essential nuclear localization sequence in Mcm3

Z Wang, YJ Zhang, Q Zhang, K Bilsborrow… - PLoS …, 2025 - journals.plos.org
Proteins with nuclear localization sequences (NLSs) are directed into the cell nucleus
through interactions between the NLS and importin proteins. NLSs are generally short motifs …

Multifaceted roles of SUMO in DNA metabolism

YM Thu - Nucleus, 2024 - Taylor & Francis
Sumoylation, a process in which SUMO (small ubiquitin like modifier) is conjugated to target
proteins, emerges as a post-translational modification that mediates protein− protein …