The past decade has seen an explosion in the use of DNA-based microarrays. These
techniques permit assessment of RNA abundance on a genome-wide scale. Medical …

Nearly half of patients with colorectal cancer (CRC), the third leading cause of cancer deaths
worldwide, are diagnosed in the late stages of the disease. Appropriate treatment is not …

MicroRNAs (miRNAs) are key post transcriptional regulators of their multiple target genes.
However, the detailed profile of miRNA expression in Parkinson's disease, the second most …

Background There are currently no accurate serum markers for detecting early risk of
colorectal cancer (CRC). We therefore developed a non-targeted metabolomics technology …

Colorectal cancer (CRC) is the third most common cancer in the world. A significant survival
rate is achieved if it is detected at an early stage. A whole blood screening test, without any …

Purpose More than 130 years ago, circulating tumour cells (CTCs) and disseminated tumour
cells (DTCs) have been linked to metastasis. Since then, a myriad of studies attempted to …

Our studies in children with rheumatic diseases have led to the identification of two of the
oldest cytokines, type I interferon (IFN) and interleukin 1 (IL‐1), as important pathogenic …

Background A noninvasive blood test for the early detection of colorectal cancer (CRC) is
highly required. We evaluated a panel of 4 mRNAs as putative markers of CRC. Materials …

Background Ulcerative colitis is an emerging global health concern that poses a significant
threat to human health and can progress to colorectal cancer if not diagnosed and treated …

Interleukin 1b (IL-1b) is emerging as mediator of a wide range of human diseases.
Availability of IL-1 blockers that result in clinical benefits to patients with these diseases is …