The effect and mechanism of Jiao-tai-wan in the treatment of diabetes mellitus with depression based on network pharmacology and experimental analysis
Y Tang, H Su, H Wang, F Lu, K Nie, Z Wang… - Molecular …, 2021 - Springer
Background The incidence of diabetes mellitus (DM) and depression is increasing year by
year around the world, bringing a serious burden to patients and their families. Jiao-tai-wan …
year around the world, bringing a serious burden to patients and their families. Jiao-tai-wan …
Behavioral tests for evaluating the characteristics of brain diseases in rodent models: Optimal choices for improved outcomes
L Huang, D **ao, H Sun, Y Qu… - Molecular Medicine …, 2022 - spandidos-publications.com
Behavioral assessment is the dominant approach for evaluating whether animal models of
brain diseases can successfully mimic the clinical characteristics of diseases. At present …
brain diseases can successfully mimic the clinical characteristics of diseases. At present …
[HTML][HTML] Traditional herbal formula Jiao-tai-wan improves chronic restrain stress-induced depression-like behaviors in mice
Y Tang, H Wang, K Nie, Y Gao, H Su, Z Wang… - Biomedicine & …, 2022 - Elsevier
Objectives Jiao-tai-wan (JTW) has been often used to treat insomnia and diabetes mellitus.
Recent studies found its antidepressant activity, but the related mechanism is not clear. This …
Recent studies found its antidepressant activity, but the related mechanism is not clear. This …
Organic cation transporter expression and function in the CNS
DH Sweet - Organic cation transporters in the central nervous …, 2021 - Springer
The blood–brain barrier (BBB) and blood–cerebrospinal fluid barrier (BCSFB) represent
major control checkpoints protecting the CNS, by exerting selective control over the …
major control checkpoints protecting the CNS, by exerting selective control over the …
[HTML][HTML] Merging cultures and disciplines to create a drug discovery ecosystem at Virginia commonwealth university: Medicinal chemistry, structural biology, molecular …
Abstract The Department of Medicinal Chemistry, together with the Institute for Structural
Biology, Drug Discovery and Development, at Virginia Commonwealth University (VCU) has …
Biology, Drug Discovery and Development, at Virginia Commonwealth University (VCU) has …
Larvicidal Activities of 2-Aryl-2,3-Dihydroquinazolin -4-ones against Malaria Vector Anopheles arabiensis, In Silico ADMET Prediction and Molecular Target …
Malaria, affecting all continents, remains one of the life-threatening diseases introduced by
parasites that are transmitted to humans through the bites of infected Anopheles …
parasites that are transmitted to humans through the bites of infected Anopheles …
Antitubercular, cytotoxicity, and computational target validation of dihydroquinazolinone derivatives
A series of 2, 3-dihydroquinazolin-4 (1 H)-one derivatives (3a–3m) was screened for in vitro
whole-cell antitubercular activity against the tubercular strain H37Rv and multidrug-resistant …
whole-cell antitubercular activity against the tubercular strain H37Rv and multidrug-resistant …
Organic Cation Transporters in Psychiatric Disorders
LC Daws - Organic Cation Transporters in the Central Nervous …, 2021 - Springer
Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed
medications for psychiatric disorders, yet they leave the majority of patients without full …
medications for psychiatric disorders, yet they leave the majority of patients without full …
Effect of Kruppel‐like factor 4 on PTZ‐induced acute seizure mice
B Li, J Piao, X Piao, Z Geng, Z Cheng… - Journal of Cellular …, 2024 - Wiley Online Library
Abstract Kruppel‐like factor 4 (Klf4) is a transcription factor that is involved in neuronal
regeneration and the development of glutamatergic systems. However, it is unknown …
regeneration and the development of glutamatergic systems. However, it is unknown …
Structural and functional perspectives on interactions between synthetic cathinones and monoamine transporters
VT Nguyen, AC Harris Jr, JM Eltit - Advances in Pharmacology, 2024 - Elsevier
Synthetic cathinone derivatives comprise a family of psychoactive compounds structurally
related to amphetamine. Over the last decade, clandestine chemists have synthesized a …
related to amphetamine. Over the last decade, clandestine chemists have synthesized a …