Surface-enhanced Raman spectroscopy: current understanding, challenges, and opportunities

H Ma, SQ Pan, WL Wang, X Yue, XH **, S Yan… - ACS …, 2024 - ACS Publications
While surface-enhanced Raman spectroscopy (SERS) has experienced substantial
advancements since its discovery in the 1970s, it is an opportunity to celebrate …

Visible-light and near-infrared fluorescence and surface-enhanced Raman scattering point-of-care sensing and bio-imaging: a review

Y Hang, J Boryczka, N Wu - Chemical Society Reviews, 2022 - pubs.rsc.org
This review article deals with the concepts, principles and applications of visible-light and
near-infrared (NIR) fluorescence and surface-enhanced Raman scattering (SERS) in in vitro …

In situ electrochemical regeneration of nanogap hotspots for continuously reusable ultrathin SERS sensors

SM Sibug-Torres, DB Grys, G Kang, M Niihori… - Nature …, 2024 - nature.com
Surface-enhanced Raman spectroscopy (SERS) harnesses the confinement of light into
metallic nanoscale hotspots to achieve highly sensitive label-free molecular detection that …

Fundamental understanding and applications of plasmon-enhanced Raman spectroscopy

X Wang, SC Huang, S Hu, S Yan, B Ren - Nature Reviews Physics, 2020 - nature.com
Plasmon-enhanced Raman spectroscopy (PERS), including surface-enhanced Raman
spectroscopy, shell-isolated nanoparticle-enhanced Raman spectroscopy and tip-enhanced …

Surface-enhanced Raman spectroscopy for bioanalysis: reliability and challenges

C Zong, M Xu, LJ Xu, T Wei, X Ma, XS Zheng… - Chemical …, 2018 - ACS Publications
Surface-enhanced Raman spectroscopy (SERS) inherits the rich chemical fingerprint
information on Raman spectroscopy and gains sensitivity by plasmon-enhanced excitation …

SERS nanoparticles in medicine: from label-free detection to spectroscopic tagging

LA Lane, X Qian, S Nie - Chemical reviews, 2015 - ACS Publications
The development of diagnostic and therapeutic nanoparticles for biomedical applications is
of broad current interest in science, engineering, and medicine. The fundamental basis is …

Label-free SERS in biological and biomedical applications: Recent progress, current challenges and opportunities

XS Zheng, IJ Jahn, K Weber, D Cialla-May… - Spectrochimica Acta Part …, 2018 - Elsevier
To achieve an insightful look within biomolecular processes on the cellular level, the
development of diseases as well as the reliable detection of metabolites and pathogens, a …

Ultrasensitive detection and distinction of pollutants based on SERS assisted by machine learning algorithms

S Lin, X Fang, G Fang, F Liu, H Dong, H Zhao… - Sensors and Actuators B …, 2023 - Elsevier
SERS as a promising sensing technique still faces challenges in the precise identification of
trace-amount molecules due to the limitation of sensitivity and cleanliness of SERS …

Surface-enhanced Raman spectroscopy: a half-century historical perspective

J Yi, EM You, R Hu, DY Wu, GK Liu, ZL Yang… - Chemical Society …, 2025 - pubs.rsc.org
Surface-enhanced Raman spectroscopy (SERS) has evolved significantly over fifty years
into a powerful analytical technique. This review aims to achieve five main goals.(1) …

Label-free detection of native proteins by surface-enhanced Raman spectroscopy using iodide-modified nanoparticles

LJ Xu, C Zong, XS Zheng, P Hu, JM Feng… - Analytical …, 2014 - ACS Publications
Proteins perform vital functional and structural duties in living systems, and the in-depth
investigation of protein in its native state is one of the most important challenges in the …