Background Multimorbidity and the associated use of multiple medicines (polypharmacy), is
common in the older population. Despite this, there is no consensus definition for …

Polypharmacy, defined as regular use of at least five medications, is common in older adults
and younger at-risk populations and increases the risk of adverse medical outcomes. There …

Importance Frailty is a common geriatric syndrome of significant public health importance,
yet there is limited understanding of the risk of frailty development at a population level …

Aims Frailty is a complex geriatric syndrome resulting in decreased physiological reserves.
Frailty and polypharmacy are common in older adults and the focus of extensive studies …

Objectives To summarize evidence regarding the health outcomes associated with
polypharmacy, defined as number of prescribed medications, in older community‐dwelling …

OBJECTIVE: This study aimed to determine an optimal discriminating number of
concomitant medications associated with geriatric syndromes, functional outcomes, and …

Although prescribed and over-the-counter medications may improve a wide range of health
problems, they also may cause or contribute to harm, especially in older adults. Current-day …

Malnutrition, frailty and sarcopenia are becoming increasingly prevalent among community-
dwelling older adults; yet are often unidentified and untreated in community settings. There …

Objectives To investigate the relationship between polypharmacy and frailty. Design
Longitudinal, observational cohort study. Setting Saarland, Germany. Participants 3,058 …

Purpose To assess the prevalence of polypharmacy and frailty, to examine their association,
and to establish their independent and combined effects on mortality in a sample of French …