Lubrication of articular cartilage

S Jahn, J Seror, J Klein - Annual review of biomedical …, 2016 - annualreviews.org
The major synovial joints such as hips and knees are uniquely efficient tribological systems,
able to articulate over a wide range of shear rates with a friction coefficient between the …

Additive manufacturing of tissues and organs

FPW Melchels, MAN Domingos, TJ Klein… - Progress in polymer …, 2012 - Elsevier
Additive manufacturing techniques offer the potential to fabricate organized tissue constructs
to repair or replace damaged or diseased human tissues and organs. Using these …

Biomaterials to mimic and heal connective tissues

BR Freedman, DJ Mooney - Advanced Materials, 2019 - Wiley Online Library
Connective tissue is one of the four major types of animal tissue and plays essential roles
throughout the human body. Genetic factors, aging, and trauma all contribute to connective …

Chondrogenic differentiation of mesenchymal stem cells: challenges and unfulfilled expectations

RA Somoza, JF Welter, D Correa… - Tissue Engineering Part …, 2014 - liebertpub.com
Articular cartilage repair and regeneration provides a substantial challenge in Regenerative
Medicine because of the high degree of morphological and mechanical complexity intrinsic …

[HTML][HTML] The biology of Lubricin: Near frictionless joint motion

GD Jay, KA Waller - Matrix Biology, 2014 - Elsevier
Lubricin is a surface-active mucinous glycoprotein secreted in the synovial joint that plays an
important role in cartilage integrity. In healthy joints, lubricin molecules coat the cartilage …

Cartilage biomechanics: From the basic facts to the challenges of tissue engineering

N Petitjean, P Canadas, P Royer… - … Research Part A, 2023 - Wiley Online Library
Articular cartilage (AC) is the thin tissue that covers the long bone ends in the joints and that
ensures the transmission of forces between adjacent bones while allowing nearly …

Engineering cartilage tissue

C Chung, JA Burdick - Advanced drug delivery reviews, 2008 - Elsevier
Cartilage tissue engineering is emerging as a technique for the regeneration of cartilage
tissue damaged due to disease or trauma. Since cartilage lacks regenerative capabilities, it …

[HTML][HTML] Advancements in hydrogel design for articular cartilage regeneration: A comprehensive review

F Hashemi-Afzal, H Fallahi, F Bagheri, MN Collins… - Bioactive Materials, 2025 - Elsevier
This review paper explores the cutting-edge advancements in hydrogel design for articular
cartilage regeneration (CR). Articular cartilage (AC) defects are a common occurrence …

Basic science of articular cartilage and osteoarthritis

AD Pearle, RF Warren… - Clinics in sports …, 2005 - sportsmed.theclinics.com
Osteoarthritis (OA) afflicts more than 20 million people in the United States and about 10% of
adults over the age of 50 years [1]. It has been demonstrated that 2.0% of women and 1.4 …

Rapid phenotypic changes in passaged articular chondrocyte subpopulations

EM Darling, KA Athanasiou - Journal of orthopaedic research, 2005 - Wiley Online Library
Articular chondrocytes are often expanded in vitro and then used to assist in healing
articular cartilage defects. We investigated the extent of dedifferentiation in monolayer …