Strategies to address key challenges of metallacycle/metallacage-based supramolecular coordination complexes in biomedical applications

D Xu, Y Li, S Yin, F Huang - Chemical Society Reviews, 2024 - pubs.rsc.org
Owing to their capacity for dynamically linking two or more functional molecules,
supramolecular coordination complexes (SCCs), exemplified by two-dimensional (2D) …

Antimicrobial peptides (AMPs): roles, functions and mechanism of action

R Seyfi, FA Kahaki, T Ebrahimi… - International Journal of …, 2020 - Springer
Antimicrobial peptides (AMPs) are a crucial part of innate immunity that exist in the most of
living organisms. In fact, AMPs have ability to incite the innate immune response and combat …

Nanomedicine in cancer therapy

D Fan, Y Cao, M Cao, Y Wang, Y Cao… - Signal Transduction and …, 2023 - nature.com
Cancer remains a highly lethal disease in the world. Currently, either conventional cancer
therapies or modern immunotherapies are non-tumor-targeted therapeutic approaches that …

Overcoming the biological barriers in the tumor microenvironment for improving drug delivery and efficacy

Y Zhou, X Chen, J Cao, H Gao - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
The delivery of drugs to tumors by nanoparticles is a rapidly growing field. However, the
complex tumor microenvironment (TME) barriers greatly hinder drug delivery to tumors. In …

Surface engineering of hollow gold nanoparticle with mesenchymal stem cell membrane and MUC-1 aptamer for targeted theranostic application against metastatic …

S Taghavi, H Tabasi, M Zahiri, K Abnous… - European Journal of …, 2023 - Elsevier
Mesenchymal stem cell membrane (MSCM)-coated biomimetic doxorubicin-loaded hollow
gold nanoparticles were fabricated and decorated with MUC1 aptamer in order to provide …

[HTML][HTML] Peptide-nanoparticle conjugates as a theranostic platform

S Kim, YH No, R Sluyter, K Konstantinov… - Coordination Chemistry …, 2024 - Elsevier
Theranostic platforms have emerged as advanced systems integrating diagnostic and
therapeutic agents to enable personalized medicine tailored to the specific characteristics of …

Self-assembled polymeric vesicles: Focus on polymersomes in cancer treatment

F Araste, A Aliabadi, K Abnous, SM Taghdisi… - Journal of Controlled …, 2021 - Elsevier
The progress in advanced materials using nanoscale components can be conducted by an
innovative idea involving combining nanotechnology approaches with supramolecular …

Antimicrobial peptides with anticancer activity: Today status, trends and their computational design

M Kordi, Z Borzouyi, S Chitsaz, M hadi Asmaei… - Archives of biochemistry …, 2023 - Elsevier
Some antimicrobial peptides have been shown to be able to inhibit the proliferation of
cancer cell lines. Various strategies for treating cancers with active peptides have been …

The recent advance of cell-penetrating and tumor-targeting peptides as drug delivery systems based on tumor microenvironment

Q Zhang, N Liu, J Wang, Y Liu, K Wang… - Molecular …, 2023 - ACS Publications
Cancer has become the primary reason for industrial countries death. Although first-line
treatments have achieved remarkable results in inhibiting tumors, they could have serious …

Peptide-based gene delivery vectors

Z Kang, Q Meng, K Liu - Journal of materials chemistry B, 2019 - pubs.rsc.org
Gene therapy as a strategy for disease treatment requires safe and efficient gene delivery
systems that encapsulate nucleic acids and deliver them to effective sites in the cell. Due to …