Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a natural
product class that has undergone significant expansion due to the rapid growth in genome …

Background The marine environment hosts a wide variety of species that have evolved to
live in harsh and challenging conditions. Marine organisms are the focus of interest due to …

Covering: 2006 to 2017 Actinomycetes have been, for decades, one of the most important
sources for the discovery of new antibiotics with an important number of drugs and analogs …

The emergence of multidrug resistant (MDR) pathogens is a global threat and has created
problems in providing adequate treatment of many infectious diseases. Although the …

Since ancient times, natural products from plants, animals, microbial and marine sources
have been exploited for treatment of several diseases. The knowledge of our ancestors is …

Natural products have historically been of crucial importance in the identification and
development of antibacterial agents. Interest in these systems has waned in recent years …

Covering: 2000 to 2018 The antimicrobial activity of many of their natural products has
brought prominence to the Streptomycetaceae, a family of Gram-positive bacteria that …

Natural products are a rich source of potential drugs for many applications. Discovery of
natural products through the activation of cryptic gene clusters encoding their biosynthetic …

Some bacterial clades are important sources of novel bioactive natural products. Estimating
the magnitude of chemical diversity available from such a resource is complicated by issues …

Due to the threat posed by the increase of highly resistant pathogenic bacteria, there is an
urgent need for new antibiotics; all the more so since in the last 20 years, the approval for …