Objectives We evaluated whether implementation of lockdown orders in South Africa
affected ambulatory clinic visitation in rural Kwa-Zulu Natal (KZN). Design Observational …

The landmark HIV Prevention Trials Network (HPTN) 052 trial in HIV-discordant couples
demonstrated unequivocally that treatment with antiretroviral therapy (ART) substantially …

The scale-up of antiretroviral therapy (ART) is expected to raise adult life expectancy in
populations with high HIV prevalence. Using data from a population cohort of over 101,000 …

Background Sexually transmitted infections (STIs) and bacterial vaginosis (BV) are
associated with increased transmission of HIV, and poor reproductive and sexual health …

When patients receive an intervention based on whether they score below or above some
threshold value on a continuously measured random variable, the intervention will be …

Background Many mathematical models have investigated the impact of expanding access
to antiretroviral therapy (ART) on new HIV infections. Comparing results and conclusions …

There is considerable scientific evidence supporting the use of antiretroviral therapy (ART)
in prevention of human immunodeficiency virus (HIV) and tuberculosis (TB) infections. The …

ACDIS has made important contributions to our understanding of the HIV epidemic.
However, despite significant increases in antiretroviral therapy (ART) coverage, HIV …

Background As the HIV epidemic in sub-Saharan Africa matures, evidence about the age
distribution of new HIV infections and how this distribution has changed over the epidemic is …

Over the past decade, there has been a massive scale-up of primary and secondary
prevention services to reduce the population-wide incidence of HIV. However, the impact of …