A global view of hypertensive disorders and diabetes mellitus during pregnancy

L Jiang, K Tang, LA Magee, P von Dadelszen… - Nature Reviews …, 2022 - nature.com
Two important maternal cardiometabolic disorders (CMDs), hypertensive disorders in
pregnancy (HDP)(including pre-eclampsia) and gestational diabetes mellitus (GDM), result …

Preeclampsia beyond pregnancy: long-term consequences for mother and child

HR Turbeville, JM Sasser - American Journal of Physiology …, 2020 - journals.physiology.org
Preeclampsia is defined as new-onset hypertension after the 20th wk of gestation along with
evidence of maternal organ failure. Rates of preeclampsia have steadily increased over the …

FIGO (international Federation of Gynecology and obstetrics) initiative on fetal growth: best practice advice for screening, diagnosis, and management of fetal growth …

N Melamed, A Baschat, Y Yinon… - … of Gynaecology and …, 2021 - pmc.ncbi.nlm.nih.gov
Fetal growth restriction (FGR) is defined as the failure of the fetus to meet its growth potential
due to a pathological factor, most commonly placental dysfunction. Worldwide, FGR is a …

Prevention of preeclampsia

M Ma'ayeh, MM Costantine - Seminars in Fetal and Neonatal Medicine, 2020 - Elsevier
Preeclampsia is an obstetric disorder that affects 3–8% of pregnant women and remains a
leading cause of short-and long-term neonatal and maternal morbidity and mortality …

The role of aspirin, heparin, and other interventions in the prevention and treatment of fetal growth restriction

KM Groom, AL David - American journal of obstetrics and gynecology, 2018 - Elsevier
Fetal growth restriction and related placental pathologies such as preeclampsia, stillbirth,
and placental abruption are believed to arise in early pregnancy when inadequate …

Oxidative stress in placenta: health and diseases

F Wu, FJ Tian, Y Lin - BioMed research international, 2015 - Wiley Online Library
During pregnancy, development of the placenta is interrelated with the oxygen
concentration. Embryo development takes place in a low oxygen environment until the …

Animal models of preeclampsia: causes, consequences, and interventions

KL Gatford, PH Andraweera, CT Roberts, AS Care - Hypertension, 2020 - ahajournals.org
Preeclampsia is a common pregnancy complication, affecting 2% to 8% of pregnancies
worldwide, and is an important cause of both maternal and fetal morbidity and mortality …

[HTML][HTML] New ideas for the prevention and treatment of preeclampsia and their molecular inspirations

A Sakowicz, M Bralewska… - International Journal of …, 2023 - mdpi.com
Preeclampsia (PE) is a pregnancy-specific disorder affecting 4–10% of all expectant women.
It greatly increases the risk of maternal and foetal death. Although the main symptoms …

Effects of pravastatin on human placenta, endothelium, and women with severe preeclampsia

FC Brownfoot, S Tong, NJ Hannan, NK Binder… - …, 2015 - ahajournals.org
Preeclampsia is a major pregnancy complication where excess placental release of soluble
fms-like tyrosine kinase-1 (sFlt-1) and soluble endoglin causes maternal endothelial and …

Pravastatin, proton-pump inhibitors, metformin, micronutrients, and biologics: new horizons for the prevention or treatment of preeclampsia

S Tong, J Tu'uhevaha, R Hastie, F Brownfoot… - American journal of …, 2022 - Elsevier
There has been increasing research momentum to identify new therapeutic agents for the
prevention or treatment of preeclampsia, drugs that can affect the underlying disease …