Collagen mimetic peptides (CMPs) fold into a polyproline type II triple helix, allowing the
study of the structure and function (or misfunction) of the collagen family of proteins. This …

Collagen has been widely applied as a functional biomaterial in regulating tissue
regeneration and drug delivery by participating in cell proliferation, differentiation, migration …

Although stem cell-derived extracellular vesicles (EVs) have remarkable therapeutic
potential for various diseases, the therapeutic efficacy of EVs is limited due to their …

Significant progress has been made in designing bone materials capable of directing
endogenous cells to promote vascularized bone regeneration. However, current strategies …

Implantable vascular devices are widely used in clinical treatments for various vascular
diseases. However, current approved clinical implantable vascular devices generally have …

Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) have an irreplaceable
role in the treatment of myocardial infarction (MI), which can be injected into the transplanted …

In this study, we developed a novel hybrid collagen-binding nanocarrier for potential
intraductal administration and local breast cancer treatment. The particles were formed by …

The extracellular microenvironment is a highly dynamic network of biophysical and
biochemical elements, which surrounds cells and transmits molecular signals. Extracellular …

The extracellular matrix (ECM) plays an active role in cell life through a tightly controlled
reciprocal relationship maintained by several fibrous proteins, enzymes, receptors, and …

One of the most important functions of the skin, ie, protection from mechanical damage, is
ensured by collagen fibers and their interaction with other elements in the extracellular …