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'Liking'and 'wanting'in eating and food reward: Brain mechanisms and clinical implications
It is becoming clearer how neurobiological mechanisms generate 'liking'and
'wanting'components of food reward. Mesocorticolimbic mechanisms that enhance …
'wanting'components of food reward. Mesocorticolimbic mechanisms that enhance …
Improving translation of animal models of addiction and relapse by reverse translation
Critical features of human addiction are increasingly being incorporated into complementary
animal models, including escalation of drug intake, punished drug seeking and taking …
animal models, including escalation of drug intake, punished drug seeking and taking …
Multimodal map** of cell types and projections in the central nucleus of the amygdala
The central nucleus of the amygdala (CEA) is a brain region that integrates external and
internal sensory information and executes innate and adaptive behaviors through distinct …
internal sensory information and executes innate and adaptive behaviors through distinct …
Animal models of drug relapse and craving after voluntary abstinence: a review
Relapse to drug use during abstinence is a defining feature of addiction. During the last
several decades, this clinical scenario has been studied at the preclinical level using classic …
several decades, this clinical scenario has been studied at the preclinical level using classic …
Plastic and stimulus-specific coding of salient events in the central amygdala
The central amygdala (CeA) is implicated in a range of mental processes including attention,
motivation, memory formation and extinction and in behaviours driven by either aversive or …
motivation, memory formation and extinction and in behaviours driven by either aversive or …
A neural substrate of compulsive alcohol use
Alcohol intake remains controlled in a majority of users but becomes “compulsive,” ie,
continues despite adverse consequences, in a minority who develop alcohol addiction …
continues despite adverse consequences, in a minority who develop alcohol addiction …
The protective effect of operant social reward on cocaine self-administration, choice, and relapse is dependent on delay and effort for the social reward
Social reinforcement-based treatments are effective for many, but not all, people with
addictions to drugs. We recently developed an operant rat model that mimics features of one …
addictions to drugs. We recently developed an operant rat model that mimics features of one …
Relapse after electric barrier-induced voluntary abstinence: A review
Relapse to drug use during abstinence is a defining feature of addiction. To date, however,
results from studies using rat relapse/reinstatement models have yet to result in FDA …
results from studies using rat relapse/reinstatement models have yet to result in FDA …
The protective effect of social reward on opioid and psychostimulant reward and relapse: behavior, pharmacology, and brain regions
Until recently, most modern neuroscience research on addiction using animal models did
not incorporate manipulations of social factors. Social factors play a critical role in human …
not incorporate manipulations of social factors. Social factors play a critical role in human …
Incentive motivation:'wanting'roles of central amygdala circuitry
The central nucleus of amygdala (CeA) mediates positively-valenced reward motivation as
well as negatively-valenced fear. Optogenetic or neurochemical stimulation of CeA circuitry …
well as negatively-valenced fear. Optogenetic or neurochemical stimulation of CeA circuitry …