The long-lasting success of forward genetic screens relies on the simple molecular basis of
the characterized phenotypes, which are typically caused by mutations in single genes …

Eukaryotic microbial pathogens are major contributors to illness and death globally.
Although much of their impact can be controlled by drug therapy as with prokaryotic …

Malaria parasites break down host haemoglobin into peptides and amino acids in the
digestive vacuole for export to the parasite cytoplasm for growth: interrupting this process is …

The chloroquine resistance transporter, PfCRT, of the human malaria parasite Plasmodium
falciparum is sensitive to acidic pH. Consequently, PfCRT operates at 60% of its maximal …

Abstract Background In this study, Aloe vera samples were collected from different climatic
regions of India. Quantitative HPTLC (high performance thin layer chromatography) analysis …

Membrane transport proteins, also known as transporters, control the movement of ions,
nutrients, metabolites, and waste products across the membranes of a cell and are central to …

Mainstay treatment for Plasmodium vivax malaria has long relied on chloroquine (CQ)
against blood-stage parasites plus primaquine against dormant liver-stage forms …

Infection by malaria parasites (Plasmodium spp.) remains one of the leading causes of
morbidity and mortality, especially in tropical regions of the world. Despite the availability of …

The human malaria parasite Plasmodium falciparum is globally widespread, but its
prevalence varies significantly between and even within countries. Most population genetic …

The evolution of sequencing technologies, from Sanger to next generation (NGS) and now
the emerging third generation, has prompted a radical frameshift moving genomics from the …