Angiogenesis is rapidly initiated in response to pathological conditions and is a key target
for pharmaceutical intervention in various malignancies. Anti-angiogenic therapy has …

With high level of morbidity and mortality, tumor is one of the deadliest diseases worldwide.
Aiming to tackle tumor, researchers have developed a lot of strategies. Among these …

Acquired resistance of hepatocellular carcinoma (HCC) to sorafenib (SFB) is the main
reason for the failure of SFB treatment of the cancer. Abnormal activation of the …

Hepatocellular carcinoma (HCC), one of the most prevalent types of cancers worldwide,
continues to maintain high levels of resistance to standard therapy. As clinical data revealed …

Introduction Heart failure is the final pathway for a wide spectrum of myocardial stress,
including hypertension and myocardial infarction. However, the potential effects of metformin …

Rationale: A high tumor-to-healthy-tissue uptake ratio of radiolabeled ligands is an essential
prerequisite for safe and effective peptide receptor radionuclide therapy (PRRT). In the …

Metastasis is the main cause of poor prognosis of patients with gastric cancer (GC). Thus,
current research is focused on identifying biomarkers that can predict the prognosis of …

The biguanide metformin, a widely used antidiabetic drug, has received great interest in
oncology research in recent years after an epidemiological study showed a link between …

Researchers have promoted the use of polymer microspheres in medical engineering and
biotechnology, such as embedded drug delivery with polylactic acid microspheres …

Metformin is one of the most promising drugs transitioning from current endocrinology to
future oncology. The objective of the study is to analyze the influence of glucose starvation …