The anti-tumor activity of the immune system is increasingly recognized as critical for the
mounting of a prolonged and effective response to cancer growth and invasion, and for …

The human immune system is an interaction network of biological processes, and its
dysfunction is closely associated with a wide array of diseases, such as cancer, infectious …

When the immune system responds to tumour development, patterns of immune infiltrates
emerge, highlighted by the expression of immune checkpoint-related molecules such as …

Classical mathematical models of tumor growth have shaped our understanding of cancer
and have broad practical implications for treatment scheduling and dosage. However, even …

Encouraging advances are being made in cancer immunotherapy modeling, especially in
the key areas of develo** personalized treatment strategies based on individual patient …

Cancer is still one of the major causes of death worldwide. Even if its comprehension is
improving continuously, the complexity and heterogeneity of this group of diseases …

Over the past decade, several immunotherapies have been approved for the treatment of
melanoma. The most prominent of these are the immune checkpoint inhibitors, which are …

Cancer is a complex disease, responsible for a significant portion of global deaths. The
increasing prioritisation of know-why over know-how approaches in biological research has …

Highlights•Cancer is a heterogeneous and evolving disease, yet most drugs are
administered to simply give the maximum dose.•Treatment scheduling currently ignores the …

We present a novel mathematical model involving various immune cell populations and
tumor cell populations. The model describes how tumor cells evolve and survive the brief …