Over the past two decades, nuclear magnetic resonance (NMR) has emerged as one of the
three principal analytical techniques used in metabolomics (the other two being gas …

Solid-state NMR with magic-angle spinning (MAS) is an important method in structural
biology. While NMR can provide invaluable information about local geometry on an atomic …

Hyperpolarization chemistry based on reversible exchange of parahydrogen, also known as
Signal Amplification By Reversible Exchange (SABRE), is a particularly simple approach to …

Molecular metabolic imaging in humans is dominated by positron emission tomography
(PET). An emerging nonionizing alternative is hyperpolarized MRI of 13C-pyruvate, which is …

In this review, we present the physical principles of the SABRE (Signal Amplification By
Reversible Exchange) method. SABRE is a promising hyperpolarization technique that …

Hyperpolarized fumarate is a promising biosensor for carbon-13 magnetic resonance
metabolic imaging. Such molecular imaging applications require nuclear hyperpolarization …

NMR spectroscopy is the only method to access the structural dynamics of biomolecules at
high (atomistic) resolution in their native solution state. However, this method's low …

Studying disease models at the molecular level is vital for drug development in order to
improve treatment and prevent a wide range of human pathologies. Microbial infections are …

Quantum technologies have seen a rapid developmental surge over the last couple of years.
Though often overshadowed by quantum computation, quantum sensors show tremendous …

Dissolution dynamic nuclear polarization (d-DNP) is a versatile method to enhance nuclear
magnetic resonance (NMR) spectroscopy. It boosts signal intensities by four to five orders of …