The biologically relevant coordination chemistry of iron and nitric oxide: electronic structure and reactivity

N Lehnert, E Kim, HT Dong, JB Harland… - Chemical …, 2021 - ACS Publications
Nitric oxide (NO) is an important signaling molecule that is involved in a wide range of
physiological and pathological events in biology. Metal coordination chemistry, especially …

Nitric oxide in macrophage immunometabolism: hiding in plain sight

EM Palmieri, C McGinity, DA Wink, DW McVicar - Metabolites, 2020 - mdpi.com
Nitric Oxide (NO) is a soluble endogenous gas with various biological functions like
signaling, and working as an effector molecule or metabolic regulator. In response to …

The potential of nitric oxide releasing therapies as antimicrobial agents

DO Schairer, JS Chouake, JD Nosanchuk… - Virulence, 2012 - Taylor & Francis
Nitric oxide (NO) is a short-lived, diatomic, lipophilic gas that plays an integral role in
defending against pathogens. Among its many functions are involvement in immune cell …

Nitric oxide and macrophage function

J MacMicking, Q **e, C Nathan - Annual review of immunology, 1997 - annualreviews.org
▪ Abstract At the interface between the innate and adaptive immune systems lies the high-
output isoform of nitric oxide synthase (NOS2 or iNOS). This remarkable molecular machine …

Current and recent advanced strategies for combating biofilms

M Sadekuzzaman, S Yang… - … Reviews in Food …, 2015 - Wiley Online Library
Biofilms are matrix‐enclosed microbial aggregates that adhere to a biological or
nonbiological surface. Biofilm formation is a significant problem in the medical, food, and …

Recent advances in thromboresistant and antimicrobial polymers for biomedical applications: just say yes to nitric oxide (NO)

Y Wo, EJ Brisbois, RH Bartlett, ME Meyerhoff - Biomaterials science, 2016 - pubs.rsc.org
Biomedical devices are essential for patient diagnosis and treatment; however, when blood
comes in contact with foreign surfaces or homeostasis is disrupted, complications including …

DNA deaminating ability and genotoxicity of nitric oxide and its progenitors

DA Wink, KS Kasprzak, CM Maragos, RK Elespuru… - Science, 1991 - science.org
Nitric oxide (NO), a multifaceted bioregulatory agent and an environmental pollutant, can
also cause genomic alterations. In vitro, NO deaminated deoxynucleosides …

Recent developments in nitric oxide donor drugs

MR Miller, IL Megson - British journal of pharmacology, 2007 - Wiley Online Library
During the 1980s, the free radical, nitric oxide (NO), was discovered to be a crucial
signalling molecule, with wide‐ranging functions in the cardiovascular, nervous and immune …

Photoremovable protecting groups: reaction mechanisms and applications

AP Pelliccioli, J Wirz - Photochemical & photobiological sciences, 2002 - pubs.rsc.org
Photolabile protecting groups enable biochemists to control the release of bioactive
compounds in living tissue.'Caged compounds'(photoactivatable bioagents) have become …

Does nitric oxide modulate mitochondrial energy generation and apoptosis?

S Moncada, JD Erusalimsky - Nature Reviews Molecular Cell Biology, 2002 - nature.com
The physiological role of nitric oxide (NO) in the maintenance of vascular tone, in synaptic
transmission and in cellular defence is now firmly established. Recent evidence indicates …