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[HTML][HTML] The anticancer mechanism of action of selected polyphenols in triple-negative breast cancer (TNBC)
R Farghadani, R Naidu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Breast cancer is a leadingcause of cancer-related deaths in women globally, with triple-
negative breast cancer (TNBC) being an aggressive subtype that lacks targeted therapies …
negative breast cancer (TNBC) being an aggressive subtype that lacks targeted therapies …
[HTML][HTML] Therapeutic effects of citrus flavonoids neohesperidin, hesperidin and its aglycone, hesperetin on bone health
AC Ortiz, SOM Fideles, CHB Reis, MZ Bellini… - Biomolecules, 2022 - mdpi.com
Flavonoids are natural phytochemicals that have therapeutic effects and act in the
prevention of several pathologies. These phytochemicals can be found in seeds, grains, tea …
prevention of several pathologies. These phytochemicals can be found in seeds, grains, tea …
Co-delivery of hesperetin and cisplatin via hyaluronic acid-modified liposome for targeted inhibition of aggression and metastasis of triple-negative breast cancer
X Wang, Y Song, L Yu, X Xue, M Pang… - … Applied Materials & …, 2023 - ACS Publications
Having no specific therapy for triple-negative breast cancer (TNBC), this subtype has the
lowest survival rate and highest metastatic risk of breast cancer since the tumor inflammatory …
lowest survival rate and highest metastatic risk of breast cancer since the tumor inflammatory …
Progress of research on the role of active ingredients of Citri Reticulatae Pericarpium in liver injury
S Gao, X Chen, Z Yu, R Du, B Chen, Y Wang, X Cai… - Phytomedicine, 2023 - Elsevier
Background Liver is a vital organ responsible for metabolizing and detoxifying both
endogenous and exogenous substances in the body. However, it is susceptible to damage …
endogenous and exogenous substances in the body. However, it is susceptible to damage …
Flavonoids as promising anticancer therapeutics: Contemporary research, nanoantioxidant potential, and future scope
Flavonoids are natural polyphenolic compounds considered safe, pleiotropic, and readily
available molecules. It is widely distributed in various food products such as fruits and …
available molecules. It is widely distributed in various food products such as fruits and …
[HTML][HTML] Targeting cell signaling pathways in lung cancer by bioactive phytocompounds
Simple Summary Lung cancer is the leading cause of mortality in cancer patients, causing
an estimated 1.8 million deaths in the year 2020. However, the available therapeutic options …
an estimated 1.8 million deaths in the year 2020. However, the available therapeutic options …
Various concentrations of hesperetin induce different types of programmed cell death in human breast cancerous and normal cell lines in a ROS-dependent manner
MR Samandari-Bahraseman, B Khorsand… - Chemico-Biological …, 2023 - Elsevier
The polyphenolic component of citrus fruits, hesperetin (Hst), is a metabolite of hesperidin. In
this study, we examined the effect of varying doses and exposure times of hesperetin on …
this study, we examined the effect of varying doses and exposure times of hesperetin on …
Isorhamnetin induces cell cycle arrest and apoptosis by triggering DNA damage and regulating the AMPK/mTOR/p70S6K signaling pathway in doxorubicin-resistant …
T Yang, Y **ao, S Liu, F Luo, D Tang, Y Yu, Y **e - Phytomedicine, 2023 - Elsevier
Background Acquired resistance to doxorubicin (DOX) inevitably limits its clinical use
against breast cancer (BC). Isorhamnetin (IS), a native flavonoid which extensively available …
against breast cancer (BC). Isorhamnetin (IS), a native flavonoid which extensively available …
Therapeutic implications of dietary polyphenols-loaded nanoemulsions in cancer therapy
R Tomar, SS Das, VKR Balaga, S Tambe… - ACS Applied Bio …, 2024 - ACS Publications
Cancer is one of the major causes of death worldwide, even the second foremost cause
related to non-communicable diseases. Cancer cells typically possess several cellular and …
related to non-communicable diseases. Cancer cells typically possess several cellular and …
Hesperidin suppressed metastasis, angiogenesis and tumour growth in Balb/c mice model of breast cancer
E Shakiba, A Bazi, H Ghasemi… - Journal of Cellular …, 2023 - Wiley Online Library
Considering the unfavourable response of breast cancer (BC) to treatment, we assessed the
therapeutic potential hesperidin in mice bearing 4T1 BC tumours. Anti‐tumour effects were …
therapeutic potential hesperidin in mice bearing 4T1 BC tumours. Anti‐tumour effects were …