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Macrophage polarization and the regulation of bone immunity in bone homeostasis
K Hu, Z Shang, X Yang, Y Zhang… - Journal of Inflammation …, 2023 - Taylor & Francis
Bone homeostasis is a dynamic equilibrium state of bone formation and absorption,
ensuring skeletal development and repair. Bone immunity encompasses all aspects of the …
ensuring skeletal development and repair. Bone immunity encompasses all aspects of the …
Global Literature Analysis of Organoid and Organ‐on‐Chip Research
J Shoji, RP Davis, CL Mummery… - Advanced healthcare …, 2024 - Wiley Online Library
Organoids and cells in organ‐on‐chip platforms replicate higher‐level anatomical,
physiological, or pathological states of tissues and organs. These technologies are widely …
physiological, or pathological states of tissues and organs. These technologies are widely …
The role of biomaterials and scaffolds in immune responses in regenerative medicine: macrophage phenotype modulation by biomaterial properties and scaffold …
Scaffolds are an integral part of the regenerative medicine field. The contact of biomaterials
with tissue, as was clearly observed over the years, induces immune reactions in a material …
with tissue, as was clearly observed over the years, induces immune reactions in a material …
Synovial joint-on-a-chip for modeling arthritis: progress, pitfalls, and potential
ZA Li, S Sant, SK Cho, SB Goodman, BA Bunnell… - Trends in …, 2023 - cell.com
Disorders of the synovial joint, such as osteoarthritis (OA) and rheumatoid arthritis (RA),
afflict a substantial proportion of the global population. However, current clinical …
afflict a substantial proportion of the global population. However, current clinical …
Human Mesenchymal Stem Cell‐Derived Miniature Joint System for Disease Modeling and Drug Testing
Diseases of the knee joint such as osteoarthritis (OA) affect all joint elements. An in vitro
human cell‐derived microphysiological system capable of simulating intraarticular tissue …
human cell‐derived microphysiological system capable of simulating intraarticular tissue …
Sustained release of dexamethasone from 3D-printed scaffolds modulates macrophage activation and enhances osteogenic differentiation
M Majrashi, A Kotowska, D Scurr… - … Applied Materials & …, 2023 - ACS Publications
Enhancing osteogenesis via modulating immune cells is emerging as a new approach to
address the current challenges in repairing bone defects and fractures. However, much …
address the current challenges in repairing bone defects and fractures. However, much …
Assembled/disassembled modular scaffolds for multicellular tissue engineering
X Yu, H Ma, Y Wang, J Hao, L Chen… - Advanced …, 2024 - Wiley Online Library
The behavior of tissue resident cells can be influenced by the spatial arrangement of cellular
interactions. Therefore, it is of significance to precisely control the spatial organization of …
interactions. Therefore, it is of significance to precisely control the spatial organization of …
Osteoarthritis models: From animals to tissue engineering
H Dou, S Wang, J Hu, J Song… - Journal of Tissue …, 2023 - journals.sagepub.com
Osteoarthritis (OA) is a chronic degenerative osteoarthropathy. Although it has been
revealed that a variety of factors can cause or aggravate the symptoms of OA, the …
revealed that a variety of factors can cause or aggravate the symptoms of OA, the …
Macrophage-derived exosomes promote bone mesenchymal stem cells towards osteoblastic fate through microRNA-21a-5p
K Liu, X Luo, ZY Lv, YJ Zhang, Z Meng, J Li… - … in Bioengineering and …, 2022 - frontiersin.org
The effective healing of a bone defect is dependent on the careful coordination of
inflammatory and bone-forming cells. In the current work, pro-inflammatory M1 and anti …
inflammatory and bone-forming cells. In the current work, pro-inflammatory M1 and anti …
Microsphere–Gel Composite System with Mesenchymal Stem Cell Recruitment, Antibacterial, and Immunomodulatory Properties Promote Bone Regeneration via …
S Ma, C Wang, Y Dong, W **g, P Wei… - … Applied Materials & …, 2022 - ACS Publications
Various types of biomaterials have been widely used to treat complex bone defects.
However, potential infection risks and inappropriate host immune responses induced by …
However, potential infection risks and inappropriate host immune responses induced by …