Non-alcoholic fatty liver disease (NAFLD) is one of the leading causes of chronic liver
diseases, affecting more than one-quarter of people worldwide. Hepatic steatosis can …

With current plans for manned missions to Mars and beyond, the need to better understand,
prevent, and counteract the harmful effects of long-duration spaceflight on the body is …

Patients with Alzheimer's disease (AD) display both peripheral tissue and brain insulin
resistance, the later could be a potential risk factor for cognitive dysfunction. While certain …

The sigma 2 receptor (σ2R) was described pharmacologically more than three decades ago,
but its molecular identity remained obscure until recently when it was identified as …

Chronic Trypanosoma cruzi infection leads to Chagas cardiomyopathy (CCM), with varying
manifestations such as inflammatory hypertrophic cardiomyopathy, arrhythmias, and dilated …

Abstract Ionic Liquids (ILs) are currently applied in a wide variety of fields, with promising
outcomes in microalgae high value biocompounds extraction. The occurrence of these …

Ataxia-Telangiectasia (AT) is a very rare multisystem disease of DNA repair, associated with
progressive disabling neurological symptoms, respiratory failure, immunodeficiency and …

Gonadotropin-regulated testicular RNA helicase (GRTH)/DDX25 is a member of DEAD-box
family of RNA helicase essential for the completion of spermatogenesis and male fertility, as …

One of the reported substrates for the endoplasmic reticulum (ER) translocation inhibitor
cyclotriazadisulfonamide (CADA) is DNAJC3, a chaperone of the unfolded protein response …

p58IPK is a multifaceted endoplasmic reticulum (ER) chaperone and a regulator of eIF2α
kinases involved in a wide range of cellular processes including protein synthesis, ER stress …