The Wnt/β-catenin pathway comprises a family of proteins that play critical roles in
embryonic development and adult tissue homeostasis. The deregulation of Wnt/β-catenin …

Vitamin D, traditionally known as an essential nutrient, is a precursor of a potent steroid
hormone that regulates a broad spectrum of physiological processes. In addition to its …

This is a narrative review of the evidence supporting vitamin D's anticancer actions. The first
section reviews the findings from ecological studies of cancer with respect to indices of solar …

Background & Aims Serrated polyps (SPs) and conventional adenomas are precursor
lesions for colorectal cancer (CRC), but they are believed to arise via distinct pathways. We …

Vitamin D and its active metabolites are important nutrients for human skeletal health. UV
irradiation of skin converts 7-dehydrocholesterol into vitamin D3, which metabolized in the …

The population-based association between low vitamin D status and increased cancer risk
can be inconsistent, but it is now generally accepted. These relationships link low serum …

The vitamin D receptor (VDR) is found in nearly all, if not all, cells in the body. The enzyme
that produces the active metabolite of vitamin D and ligand for VDR, namely CYP27B1 …

Despite being the most common liver cancer in children, hepatoblastoma (HB) is a rare
neoplasm. Consequently, few pretreatment tumors have been molecularly profiled, and …

PURPOSE: Higher serum levels of the main circulating form of vitamin D, 25-hydroxyvitamin
D (25 (OH) D), are associated with substantially lower incidence rates of colon, breast …

Covering: up to 2012 Steroids, a widespread class of natural organic compounds occurring
in animals, plants and fungi, have shown great therapeutic value for a broad array of …