Drug resistance is the main obstacle to achieving a cure in many cancer patients. Reactive
oxygen species (ROS) are master regulators of cancer development that act through …

Over the past few decades, research on cancer immunotherapy has firmly established
immune cells as key players in effective cancer treatment. Peptide vaccines directly targeting …

Immune checkpoint inhibitors (ICIs), including anti-cytotoxic T-lymphocyte-associated
protein 4 (CTLA-4) and anti-programmed death-1 (PD-1) antibodies, have initiated a new …

Solid tumours exhibit a well‐defined architecture, comprising a differentiated core and a
dynamic border that interfaces with the surrounding tissue. This border, characterised by …

Melanoma is the most aggressive subtype of cancer, with a higher propensity to spread
compared to most solid tumors. The application of OMICS approaches has revolutionized …

Malignant melanoma is characterized by high immunogenicity, genetic heterogeneity, and
diverse pathological manifestations, affecting both skin and mucosa over the body …

Copy number alterations (CNAs) are significant in tumor initiation and progression.
Identifying these aberrations is crucial for targeted therapies and personalized cancer …

Dear Editor, Through whole-exome sequencing (WES), we identified genomic features that
correlated with pathologic lymph node metastasis (pN) and poor patient prognosis in …

Skin cancer is a prevalent and heterogenous disease with several subtypes, such as
melanoma, basal cell carcinoma, and squamous cell carcinoma. Among them, melanoma is …

Endometrial carcinoma (EC) with deficient DNA mismatch repair (dMMR) is a specific
molecular entity with unique clinicopathological features. Herein, we depicted the mutation …