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Emerging time-resolved x-ray diffraction approaches for protein dynamics
DR Hekstra - Annual review of biophysics, 2023 - annualreviews.org
Proteins guide the flows of information, energy, and matter that make life possible by
accelerating transport and chemical reactions, by allosterically modulating these reactions …
accelerating transport and chemical reactions, by allosterically modulating these reactions …
[HTML][HTML] BioCARS: Synchrotron facility for probing structural dynamics of biological macromolecules
A major goal in biomedical science is to move beyond static images of proteins and other
biological macromolecules to the internal dynamics underlying their function. This level of …
biological macromolecules to the internal dynamics underlying their function. This level of …
Structural dynamics of protein-protein association involved in the light-induced transition of Avena sativa LOV2 protein
C Kim, SR Yun, SJ Lee, SO Kim, H Lee, J Choi… - Nature …, 2024 - nature.com
The Light-oxygen-voltage-sensing domain (LOV) superfamily, found in enzymes and signal
transduction proteins, plays a crucial role in converting light signals into structural signals …
transduction proteins, plays a crucial role in converting light signals into structural signals …
Early Folding Dynamics of i-Motif DNA Revealed by pH-Jump Time-Resolved X-ray Solution Scattering
The i-motif is a pH-responsive cytosine-rich oligonucleotide sequence that forms, under
acidic conditions, a quadruplex structure. This tunable structural switching has made the i …
acidic conditions, a quadruplex structure. This tunable structural switching has made the i …
Real-time structural characterization of protein response to a caged compound by fast detector readout and high-brilliance synchrotron radiation
K Magkakis, F Orädd, B Ahn, V Da Silva, R Appio… - Structure, 2024 - cell.com
Protein dynamics are essential to biological function, and methods to determine such
structural rearrangements constitute a frontier in structural biology. Synchrotron radiation …
structural rearrangements constitute a frontier in structural biology. Synchrotron radiation …
[HTML][HTML] Structural dynamics of proteins explored via time-resolved x-ray liquidography
The structure of a protein is closely related to its biological function. In this regard, structural
changes, as well as static structures, have been scrutinized as essential elements in …
changes, as well as static structures, have been scrutinized as essential elements in …
Cryo-EM structures of a bathy phytochrome histidine kinase reveal a unique light-dependent activation mechanism
Phytochromes are photoreceptor proteins in plants, fungi, and bacteria. They can adopt two
photochromic states with differential biochemical responses. The structural changes …
photochromic states with differential biochemical responses. The structural changes …
Unassisted stimulation of autotrophic ethanol bioproduction by visible light
W Rao, Y Kang, H Zheng, M Ye, Z Liu… - Sustainable Energy & …, 2023 - pubs.rsc.org
Illuminated semiconductors stimulate CO2 bioconversion by acetogens and other
autotrophic microorganisms. Visible light by itself is known to alter the lifestyle of non …
autotrophic microorganisms. Visible light by itself is known to alter the lifestyle of non …
BL03HB: a Laue microdiffraction beamline for both protein crystallography and materials science at SSRF
ZJ Wang, SS Wang, ZH Su, L Yu, YZ Wang… - Nuclear Science and …, 2024 - Springer
A Laue microdiffraction beamline (BL03HB) was constructed at the Shanghai Synchrotron
Radiation Facility (SSRF). This beamline features two consecutive focusing points in two …
Radiation Facility (SSRF). This beamline features two consecutive focusing points in two …
Analogies and differences in the photoactivation mechanism of bathy and canonical bacteriophytochromes revealed by multiscale modeling
Bacteriophytochromes are light-sensing biological machines that switch between two
photoreversible states, Pr and Pfr. Their relative stability is opposite in canonical and bathy …
photoreversible states, Pr and Pfr. Their relative stability is opposite in canonical and bathy …