[HTML][HTML] Engineering customized nanovaccines for enhanced cancer immunotherapy

J Guo, C Liu, Z Qi, T Qiu, J Zhang, H Yang - Bioactive Materials, 2024 - Elsevier
Nanovaccines have gathered significant attention for their potential to elicit tumor-specific
immunological responses. Despite notable progress in tumor immunotherapy, nanovaccines …

Surfactant-Mediated Assembly of Precision-Size Liposomes

IS Pires, JR Suggs, IS Carlo, DS Yun… - Chemistry of …, 2024 - ACS Publications
Liposomes can greatly improve the pharmacokinetics of therapeutic agents due to their
ability to encapsulate drugs and accumulate in target tissues. Considerable effort has been …

Charge‐Stabilized Nanodiscs as a New Class of Lipid Nanoparticles

IS Pires, A Hostetler, G Covarrubias, IS Carlo… - Advanced …, 2024 - Wiley Online Library
Nanoparticles have the potential to improve disease treatment and diagnosis due to their
ability to incorporate drugs, alter pharmacokinetics, and enable tissue targeting. While …

Dose-dependent regulation of immune memory responses against HIV by saponin monophosphoryl lipid A nanoparticle adjuvant

P Ramezani-Rad, E Marina-Zárate, L Maiorino… - bioRxiv, 2024 - biorxiv.org
The induction of durable protective immune responses is the main goal of prophylactic
vaccines, and adjuvants play an important role as drivers of such responses. Despite …

[HTML][HTML] Modulating immune responses for enhanced cell therapies: The dual role of multi-scale biomaterials

Y **, Y Ao, W Li, K Liang, H Chen, Y Long, Y Du - EngMedicine, 2024 - Elsevier
The efficacy of cell therapy is compromised by the suboptimal survival and function of
transplanted cells, which can be partly attributed to uncontrolled immunomodulation. To …

[HTML][HTML] Fractionation, purification and downstream processing: the path to commercialisation

R Abbenhuis - European Pharmaceutical …, 2024 - europeanpharmaceuticalreview.com
With increasing progress in the life sciences, we are now able to treat diseases that were
previously deemed incurable. This progress, however, comes with new challenges due to …