Radiotherapy resistance: identifying universal biomarkers for various human cancers
I Larionova, M Rakina, E Ivanyuk, Y Trushchuk… - Journal of cancer …, 2022 - Springer
Radiotherapy (RT) is considered as a standard in the treatment of most solid cancers,
including glioblastoma, lung, breast, rectal, prostate, colorectal, cervical, esophageal, and …
including glioblastoma, lung, breast, rectal, prostate, colorectal, cervical, esophageal, and …
The emerging roles of ATP-dependent chromatin remodeling complexes in pancreatic cancer
Pancreatic cancer is an aggressive cancer with low survival rates. Genetic and epigenetic
dysregulation has been associated with the initiation and progression of pancreatic tumors …
dysregulation has been associated with the initiation and progression of pancreatic tumors …
Knockdown of circ_0006528 suppresses cell proliferation, migration, invasion, and adriamycin chemoresistance via regulating the miR-1236-3p/CHD4 axis in breast …
J Hao, X Du, F Lv, Q Shi - Journal of Surgical Research, 2021 - Elsevier
Background Adriamycin (ADM) is one of the postoperative chemotherapy drugs for breast
cancer (BCa) patients. Circular RNAs have been shown to modulate ADM resistance in …
cancer (BCa) patients. Circular RNAs have been shown to modulate ADM resistance in …
CHD4 regulates platinum sensitivity through MDR1 expression in ovarian cancer: A potential role of CHD4 inhibition as a combination therapy with platinum agents
Y Oyama, S Shigeta, H Tokunaga, K Tsuji… - PLoS …, 2021 - journals.plos.org
Platinum sensitivity is an important prognostic factor in patients with ovarian cancer.
Chromodomain-helicase-DNA-binding protein 4 (CHD4) is a core member of the …
Chromodomain-helicase-DNA-binding protein 4 (CHD4) is a core member of the …
The epigenetic factor CHD4 contributes to metastasis by regulating the EZH2/β-catenin axis and acts as a therapeutic target in ovarian cancer
J Wang, F Zhong, J Li, H Yue, W Li, X Lu - Journal of Translational …, 2023 - Springer
Background The overall survival rate of patients with advanced ovarian cancer (OC) has
remained static for several decades. Advanced ovarian cancer is known for its poor …
remained static for several decades. Advanced ovarian cancer is known for its poor …
[HTML][HTML] CHD4 mediates SOX2 transcription through TRPS1 in luminal breast cancer
J Zhang, X Lv, B Wei, X Gong, L Chen - Cellular Signalling, 2022 - Elsevier
Chromodomain helicase DNA binding protein 4 (CHD4), as a core component of the
nucleosome remodeling and deactetylase (NuRD) complex, participated in the inititation …
nucleosome remodeling and deactetylase (NuRD) complex, participated in the inititation …
[HTML][HTML] CHD4 as an important mediator in regulating the malignant behaviors of colorectal cancer
CL Chang, CR Huang, SJ Chang, CC Wu… - … Journal of Biological …, 2021 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) has ranked first in terms of incidence in Taiwan. Surgical resection
combined with chemo-, radio-, or targeted-therapies are the main treatments for CRC …
combined with chemo-, radio-, or targeted-therapies are the main treatments for CRC …
[HTML][HTML] Correlation between mismatch repair statuses and the prognosis of stage I–IV colorectal cancer
G Tong, G Zhang, Y Hu, X Xu, Y Wang - Frontiers in oncology, 2024 - frontiersin.org
Background The role of microsatellite instability (MSI) and prognosis for stage II–III colorectal
cancer (CRC) has been described, but the role of MSI in stage I and IV CRC is controversial …
cancer (CRC) has been described, but the role of MSI in stage I and IV CRC is controversial …
High expression of VSTM2L induced resistance to chemoradiotherapy in rectal cancer through downstream IL‐4 signaling
H Liu, Z Zhang, P Zhen, M Zhou - Journal of immunology …, 2021 - Wiley Online Library
Background. Preoperative chemoradiotherapy (pCRT) is a common and essential
therapeutic strategy for patients with locally advanced rectal cancer (LARC), but poor tumor …
therapeutic strategy for patients with locally advanced rectal cancer (LARC), but poor tumor …
CHD4 acts as a prognostic factor and drives radioresistance in HPV negative HNSCC
F Geyer, M Geyer, U Reuning, S Klapproth, KD Wolff… - Scientific Reports, 2024 - nature.com
Despite great efforts in improving existing therapies, the outcome of patients with advanced
radioresistant HPV-negative head and neck squamous cell carcinoma (HNSCC) remains …
radioresistant HPV-negative head and neck squamous cell carcinoma (HNSCC) remains …