2024 ESC guidelines for the management of chronic coronary syndromes: developed by the task force for the management of chronic coronary syndromes of the …

C Vrints, F Andreotti, KC Koskinas… - European heart …, 2024‏ - academic.oup.com
• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

[HTML][HTML] The role of inflammation in cardiovascular disease

MY Henein, S Vancheri, G Longo… - International journal of …, 2022‏ - mdpi.com
Atherosclerosis is a chronic inflammatory disease, in which the immune system has a
prominent role in its development and progression. Inflammation-induced endothelial …

2023 AHA/ACC/ACCP/ASPC/NLA/PCNA guideline for the management of patients with chronic coronary disease: a report of the American Heart Association …

Writing Committee Members, SS Virani… - Journal of the American …, 2023‏ - jacc.org
Abstract Aim The “2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management
of Patients With Chronic Coronary Disease” provides an update to and consolidates new …

Inflammation and cholesterol as predictors of cardiovascular events among patients receiving statin therapy: a collaborative analysis of three randomised trials

PM Ridker, DL Bhatt, AD Pradhan, RJ Glynn… - The Lancet, 2023‏ - thelancet.com
Background Inflammation and hyperlipidaemia jointly contribute to atherothrombotic
disease. However, when people are treated with intensive statin therapy, the relative …

[HTML][HTML] The role of oxidative stress in atherosclerosis

M Batty, MR Bennett, E Yu - Cells, 2022‏ - mdpi.com
Atherosclerosis is a chronic inflammatory disease of the vascular system and is the leading
cause of cardiovascular diseases worldwide. Excessive generation of reactive oxygen …

Trained immunity—basic concepts and contributions to immunopathology

J Ochando, WJM Mulder, JC Madsen… - Nature Reviews …, 2023‏ - nature.com
Trained immunity is a functional state of the innate immune response and is characterized
by long-term epigenetic reprogramming of innate immune cells. This concept originated in …

Drugging the NLRP3 inflammasome: from signalling mechanisms to therapeutic targets

L Vande Walle, M Lamkanfi - Nature Reviews Drug Discovery, 2024‏ - nature.com
Diseases associated with chronic inflammation constitute a major health burden across the
world. As central instigators of the inflammatory response to infection and tissue damage …

Regulated cell death in myocardial ischemia–reperfusion injury

Q **ang, X Yi, XH Zhu, X Wei, DS Jiang - Trends in Endocrinology & …, 2024‏ - cell.com
Myocardial ischemia–reperfusion (I/R) injury most commonly occurs in coronary artery
disease when prompt reperfusion is used to salvage the ischemic myocardium …

The role of pro-inflammatory cytokines in the pathogenesis of cardiovascular disease

H Zhang, NS Dhalla - International Journal of Molecular Sciences, 2024‏ - mdpi.com
With cardiovascular disease (CVD) being a primary source of global morbidity and mortality,
it is crucial that we understand the molecular pathophysiological mechanisms at play …

Signaling pathways and targeted therapy for myocardial infarction

Q Zhang, L Wang, S Wang, H Cheng, L Xu… - Signal transduction and …, 2022‏ - nature.com
Although the treatment of myocardial infarction (MI) has improved considerably, it is still a
worldwide disease with high morbidity and high mortality. Whilst there is still a long way to …