The bioavailability of drugs from oral formulations is influenced by many physiological
factors including gastrointestinal fluid composition, pH and dynamics, transit and motility …

This paper deals with the physical and mathematical modelling description of drug release
from matrix systems. In the introduction, matrix systems are considered in the wide frame of …

Controlled release systems have been developed to improve the temporal and spatial
presentation of drug in the body, to protect drug from physiological degradation or …

Abstract Xanthan-Chitosan (X-Ch) polysaccharides nanofibers were prepared using
electrospinning processing as an encapsulation and delivery system of curcumin (Cu). The …

A systematic approach was used to demonstrate the quantitative interplay of pH, pK a,
lipophilicity, charged and uncharged molecular species, molecular size, aqueous diffusivity …

A key component of efforts to identify the biological and drug-specific aspects contributing to
therapeutic failure or unexpected exposure-associated toxicity is the study of drug–intestinal …

The buccal mucosa provides an alternative route of drug delivery that can be more
beneficial compared to other administration routes. Although numerous studies and reviews …

Several locally acting colon-targeted products to treat colonic diseases have been recently
developed and marketed, taking advantage of gastrointestinal physiology to target delivery …

Purpose The goal of the study was to evaluate a miniaturized dissolution-permeation
apparatus (μFLUX™ apparatus) for its ability to benchmark several itraconazole (ITZ) …

Animal performance is determined by the functionality and health of the gastrointestinal tract
(GIT). Complex mechanisms and interactions are involved in the regulation of GIT …