Clinical translation of nanomedicines: Challenges, opportunities, and keys
Despite the massive interest and recent developments in the field of nanomedicine, only a
limited number of formulations have found their way to the clinics. This shortcoming reveals …
limited number of formulations have found their way to the clinics. This shortcoming reveals …
Extrahepatic targeting of lipid nanoparticles in vivo with intracellular targeting for future nanomedicines
T Nakamura, Y Sato, Y Yamada… - Advanced drug delivery …, 2022 - Elsevier
A new era of nanomedicines that involve nucleic acids/gene therapy has been opened after
two decades in 21st century and new types of more efficient drug delivery systems (DDS) …
two decades in 21st century and new types of more efficient drug delivery systems (DDS) …
Mucoadhesive formulations: Innovations, merits, drawbacks, and future outlook
Mucosa has now been recognized as a potential site for both local and systemic delivery of
therapeutics. Mucoadhesive drug delivery systems with customizable release profiles have …
therapeutics. Mucoadhesive drug delivery systems with customizable release profiles have …
Chitosan-capped silver nanoparticles with potent and selective intrinsic activity against the breast cancer cells
Herein, we report on the development of chitosan-capped silver nanoparticles (AgNPs-CHI)
with an intrinsic activity against breast cancer cells. Following chemical synthesis via a …
with an intrinsic activity against breast cancer cells. Following chemical synthesis via a …
Impact of the functional coating of silver nanoparticles on their in vivo performance and biosafety
Objective and significance Silver nanoparticles (AgNPs) have become an interesting
therapeutic modality and drug delivery platform. Herein, we aimed to investigate the impact …
therapeutic modality and drug delivery platform. Herein, we aimed to investigate the impact …
Nanoformulations in the treatment of lung cancer: current status and clinical potential
Objective Recent developments in nanotechnology have regained hope in enabling the
eradication of lung cancer, while overcoming the drawbacks of the classic therapeutics …
eradication of lung cancer, while overcoming the drawbacks of the classic therapeutics …
Enhancing the low oral bioavailability of sulpiride via fast orally disintegrating tablets: formulation, optimization and in vivo characterization
Sulpiride (SUL) is a dopamine D2-receptor antagonist used for management of GIT
disturbance and it has anti-psychotic activities based on the administered dose. SUL …
disturbance and it has anti-psychotic activities based on the administered dose. SUL …
One‐pot synthesis of fluorescent nitrogen and sulfur–carbon quantum dots as a sensitive nanosensor for trimetazidine determination
Water‐soluble and highly stable N, S‐doped CQDs (N, S‐CQDs) were synthesized using a
low‐cost strategy with citric acid and thiosemicarbazide in one step for use as a fluorescent …
low‐cost strategy with citric acid and thiosemicarbazide in one step for use as a fluorescent …
Implementation of Quality by Design of Sublingual Antihypertensive Drugs
Background Hypertension poses a global health challenge, contributing significantly to
mortality and cardiovascular diseases in both developed and low-to middle-income nations …
mortality and cardiovascular diseases in both developed and low-to middle-income nations …
Implementing Quality by Design for Development and Optimization of Sublingual Tablet of Valsartan
Purpose Heart failure, a progressive cardiovascular disorder, significantly affects patient
morbidity and mortality. Valsartan, an angiotensin II receptor antagonist, is widely used to …
morbidity and mortality. Valsartan, an angiotensin II receptor antagonist, is widely used to …