Integrating liquid biopsies into the management of cancer

G Siravegna, S Marsoni, S Siena… - Nature reviews Clinical …, 2017 - nature.com
During cancer progression and treatment, multiple subclonal populations of tumour cells
compete with one another, with selective pressures leading to the emergence of …

Progress and prospects of early detection in lung cancer

S Blandin Knight, PA Crosbie, H Balata… - Open …, 2017 - royalsocietypublishing.org
Lung cancer is the leading cause of cancer-related death in the world. It is broadly divided
into small cell (SCLC, approx. 15% cases) and non-small cell lung cancer (NSCLC, approx …

Nanoparticle probes for the detection of cancer biomarkers, cells, and tissues by fluorescence

AB Chinen, CM Guan, JR Ferrer, SN Barnaby… - Chemical …, 2015 - ACS Publications
Cancer is the second most common cause of death in the United States, trailing only heart
disease in incidence. Despite significant worldwide investment in research, cancer remains …

American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer

L Harris, H Fritsche, R Mennel, L Norton… - Journal of clinical …, 2007 - ascopubs.org
Purpose To update the recommendations for the use of tumor marker tests in the prevention,
screening, treatment, and surveillance of breast cancer. Methods For the 2007 update, an …

Blood-based cancer biomarkers in liquid biopsy: a promising non-invasive alternative to tissue biopsy

J Marrugo-Ramírez, M Mir, J Samitier - International journal of molecular …, 2018 - mdpi.com
Cancer is one of the greatest threats facing our society, being the second leading cause of
death globally. Currents strategies for cancer diagnosis consist of the extraction of a solid …

Circulating tumor cells: approaches to isolation and characterization

M Yu, S Stott, M Toner, S Maheswaran… - Journal of Cell …, 2011 - rupress.org
Circulating tumor cells (CTCs) shed from primary and metastatic cancers are admixed with
blood components and are thus rare, making their isolation and characterization a major …

Tumorigenicity and genetic profiling of circulating tumor cells in small-cell lung cancer

CL Hodgkinson, CJ Morrow, Y Li, RL Metcalf… - Nature medicine, 2014 - nature.com
Small-cell lung cancer (SCLC), an aggressive neuroendocrine tumor with early
dissemination and dismal prognosis, accounts for 15–20% of lung cancer cases and∼ …

Detection of circulating tumor cells in peripheral blood of patients with metastatic breast cancer: a validation study of the CellSearch system

S Riethdorf, H Fritsche, V Müller, T Rau… - Clinical cancer …, 2007 - AACR
Abstract Purpose: The CellSearch system (Veridex, Warren, NJ) is designed to enrich and
enumerate circulating tumor cells (CTCs) from peripheral blood. Here, we validated the …

Prognostic and predictive biomarkers in breast cancer: Past, present and future

A Nicolini, P Ferrari, MJ Duffy - Seminars in cancer biology, 2018 - Elsevier
Following a diagnosis of breast cancer, the most immediate challenges in patient
management are the determination of prognosis and identification of the most appropriate …

[HTML][HTML] Circulating tumor cell technologies

MM Ferreira, VC Ramani, SS Jeffrey - Molecular oncology, 2016 - Elsevier
Circulating tumor cells, a component of the “liquid biopsy”, hold great potential to transform
the current landscape of cancer therapy. A key challenge to unlocking the clinical utility of …