Induction of epigenetic alterations by dietary and other environmental factors

JC Mathers, G Strathdee, CL Relton - Advances in genetics, 2010 - Elsevier
Dietary and other environmental factors induce epigenetic alterations which may have
important consequences for cancer development. This chapter summarizes current …

Ionizing radiation and human health: Reviewing models of exposure and mechanisms of cellular damage. An epigenetic perspective

E Burgio, P Piscitelli, L Migliore - International journal of environmental …, 2018 - mdpi.com
We reviewed available evidence in medical literature concerning experimental models of
exposure to ionizing radiations (IR) and their mechanisms of producing damages on living …

Mechanisms of radiation bystander and non-targeted effects: implications to radiation carcinogenesis and radiotherapy

R Yahyapour, E Motevaseli, A Rezaeyan… - Current …, 2018 - ingentaconnect.com
Background: Knowledge of radiobiology is of paramount importance to be able to grasp and
have an in-depth understanding of the consequences of ionizing radiation. One of the most …

[HTML][HTML] The mechanisms of radiation-induced bystander effect

M Najafi, R Fardid, GH Hadadi… - Journal of biomedical …, 2014 - ncbi.nlm.nih.gov
The radiation-induced bystander effect is the phenomenon which non-irradiated cells exhibit
effects along with their different levels as a result of signals received from nearby irradiated …

On the complexity of mechanisms and consequences of chromothripsis: an update

AS Koltsova, AA Pendina, OA Efimova… - Frontiers in …, 2019 - frontiersin.org
In the present review, we focus on the phenomenon of chromothripsis, a new type of
complex chromosomal rearrangements. We discuss the challenges of chromothripsis …

Ionizing radiation induces transgenerational effects of DNA methylation in zebrafish

JH Kamstra, S Hurem, LM Martin, LC Lindeman… - Scientific reports, 2018 - nature.com
Ionizing radiation is known to cause DNA damage, yet the mechanisms underlying potential
transgenerational effects of exposure have been scarcely studied. Previously, we observed …

Epigenetics in radiation biology: a new research frontier

M Merrifield, O Kovalchuk - Frontiers in genetics, 2013 - frontiersin.org
The number of people that receive exposure to ionizing radiation (IR) via occupational,
diagnostic, or treatment-related modalities is progressively rising. It is now accepted that the …

Non-targeted radiation effects—an epigenetic connection

Y Ilnytskyy, O Kovalchuk - Mutation Research/Fundamental and Molecular …, 2011 - Elsevier
Ionizing radiation (IR) is a pivotal diagnostic and treatment modality, yet it is also a potent
genotoxic agent that causes genome instability and carcinogenesis. While modern cancer …

Radiation‐induced bystander effects in vivo are epigenetically regulated in a tissue‐specific manner

Y Ilnytskyy, I Koturbash… - Environmental and …, 2009 - Wiley Online Library
Exposure of animal body parts to ionizing radiation (IR) can lead to molecular changes in
distant shielded “bystander” tissues and organs. Nevertheless, tissue specificity of bystander …

Hormesis and epigenetics: is there a link?

AM Vaiserman - Ageing research reviews, 2011 - Elsevier
Epigenetic regulation of gene expression is a key molecular mechanism linking
environmental factors with the genome with consequences for health status throughout the …