Differential scanning calorimetry: An invaluable tool for a detailed thermodynamic characterization of macromolecules and their interactions
MH Chiu, EJ Prenner - Journal of Pharmacy and Bioallied …, 2011 - journals.lww.com
Abstract Differential Scanning Calorimetry (DSC) is a highly sensitive technique to study the
thermotropic properties of many different biological macromolecules and extracts. Since its …
thermotropic properties of many different biological macromolecules and extracts. Since its …
Biomembrane lipids: When physics and chemistry join to shape biological activity
Biomembranes constitute the first lines of defense of cells. While small molecules can often
permeate cell walls in bacteria and plants, they are generally unable to penetrate the barrier …
permeate cell walls in bacteria and plants, they are generally unable to penetrate the barrier …
[HTML][HTML] Phosphatidylethanolamine-phosphatidylglycerol bilayer as a model of the inner bacterial membrane
Phosphatidylethanolamine (PE) and phosphatidylglycerol (PG) are the main lipid
components of the inner bacterial membrane. A computer model for such a membrane was …
components of the inner bacterial membrane. A computer model for such a membrane was …
[HTML][HTML] Molecular structures of fluid phase phosphatidylglycerol bilayers as determined by small angle neutron and X-ray scattering
We have determined the molecular structures of commonly used phosphatidylglycerols
(PGs) in the commonly accepted biologically relevant fluid phase. This was done by …
(PGs) in the commonly accepted biologically relevant fluid phase. This was done by …
Membrane-related effects underlying the biological activity of the anthraquinones emodin and barbaloin
DS Alves, L Pérez-Fons, A Estepa, V Micol - Biochemical pharmacology, 2004 - Elsevier
Commercial plant extracts containing anthraquinones are being increasingly used for
cosmetics, food and pharmaceuticals due to their wide therapeutic and pharmacological …
cosmetics, food and pharmaceuticals due to their wide therapeutic and pharmacological …
[HTML][HTML] Lipid bilayer pre-transition as the beginning of the melting process
We investigate the bilayer pre-transition exhibited by some lipids at temperatures below their
main phase transition, and which is generally associated to the formation of periodic ripples …
main phase transition, and which is generally associated to the formation of periodic ripples …
Membrane interaction and perturbation mechanisms induced by two cationic cell penetrating peptides with distinct charge distribution
ID Alves, N Goasdoué, I Correia, S Aubry… - … et Biophysica Acta (BBA …, 2008 - Elsevier
Independently from the cell penetrating peptide uptake mechanism (endocytic or not), the
interaction of the peptide with the lipid bilayer remains a common issue that needs further …
interaction of the peptide with the lipid bilayer remains a common issue that needs further …
Protein structure prediction and design in a biologically realistic implicit membrane
Protein design is a powerful tool for elucidating mechanisms of function and engineering
new therapeutics and nanotechnologies. Although soluble protein design has advanced …
new therapeutics and nanotechnologies. Although soluble protein design has advanced …
Amphiphilic indole derivatives as antimycobacterial agents: structure–activity relationships and membrane targeting properties
Antibacterials that disrupt cell membrane function have the potential to eradicate “persister”
organisms and delay the emergence of resistance. Here we report the antimycobacterial …
organisms and delay the emergence of resistance. Here we report the antimycobacterial …
Role of phosphatidylglycerols in the stability of bacterial membranes
An extensive 100-ns molecular dynamics simulation of lipid bilayer composed of mixture of
phosphatidylethanolamine (PE) and phosphatidylglycerol (PG) was performed to elucidate …
phosphatidylethanolamine (PE) and phosphatidylglycerol (PG) was performed to elucidate …