Y and W chromosome assemblies: approaches and discoveries

M Tomaszkiewicz, P Medvedev, KD Makova - Trends in genetics, 2017 - cell.com
Hundreds of vertebrate genomes have been sequenced and assembled to date. However,
most sequencing projects have ignored the sex chromosomes unique to the heterogametic …

[HTML][HTML] Genetic diversity on the sex chromosomes

MAW Sayres - Genome biology and evolution, 2018 - ncbi.nlm.nih.gov
Levels and patterns of genetic diversity can provide insights into a population's history. In
species with sex chromosomes, differences between genomic regions with unique …

Chimpanzee genomic diversity reveals ancient admixture with bonobos

M De Manuel, M Kuhlwilm, P Frandsen, VC Sousa… - Science, 2016 - science.org
Our closest living relatives, chimpanzees and bonobos, have a complex demographic
history. We analyzed the high-coverage whole genomes of 75 wild-born chimpanzees and …

The evolutionary history of Neanderthal and Denisovan Y chromosomes

M Petr, M Hajdinjak, Q Fu, E Essel, H Rougier… - Science, 2020 - science.org
Ancient DNA has provided new insights into many aspects of human history. However, we
lack comprehensive studies of the Y chromosomes of Denisovans and Neanderthals …

Pong: fast analysis and visualization of latent clusters in population genetic data

AA Behr, KZ Liu, G Liu-Fang, P Nakka… - …, 2016 - academic.oup.com
Motivation: A series of methods in population genetics use multilocus genotype data to
assign individuals membership in latent clusters. These methods belong to a broad class of …

A structure-informed atlas of human-virus interactions

G Lasso, SV Mayer, ER Winkelmann, T Chu, O Elliot… - Cell, 2019 - cell.com
While knowledge of protein-protein interactions (PPIs) is critical for understanding virus-host
relationships, limitations on the scalability of high-throughput methods have hampered their …

Population dynamics and genetic connectivity in recent chimpanzee history

C Fontsere, M Kuhlwilm, C Morcillo-Suarez… - Cell Genomics, 2022 - cell.com
Knowledge on the population history of endangered species is critical for conservation, but
whole-genome data on chimpanzees (Pan troglodytes) is geographically sparse. Here, we …

Genetic diversity on the sex chromosomes

MA Wilson Sayres - Genome Biology and Evolution, 2018 - academic.oup.com
Levels and patterns of genetic diversity can provide insights into a population's history. In
species with sex chromosomes, differences between genomic regions with unique …

Gelada genomes highlight events of gene flow, hybridisation and local adaptation that track past climatic changes

M Caldon, G Mutti, A Mondanaro, H Imai… - Molecular …, 2024 - Wiley Online Library
Theropithecus gelada, the last surviving species of this genus, occupy a unique and highly
specialised ecological niche in the Ethiopian highlands. A subdivision into three …

Selection has countered high mutability to preserve the ancestral copy number of Y chromosome amplicons in diverse human lineages

LS Teitz, T Pyntikova, H Skaletsky, DC Page - The American Journal of …, 2018 - cell.com
Amplicons—large, highly identical segmental duplications—are a prominent feature of
mammalian Y chromosomes. Although they encode genes essential for fertility, these …