Nucleic acid aptamers are single-stranded DNA or RNA of 20–100 nucleotides in length that
have attracted substantial scientific interest due to their ability to specifically bind to target …

Nucleic acids are remarkable molecules. In addition to Watson–Crick base pairing, the
different structural motifs of these molecules can bind non‐nucleic acid targets or catalyze …

In the arena of material sciences, one of the burning topics for research has been
biogenically synthesizing nanoparticles (NPs) from plant derivatives and studying their …

SELEX stands for systematic evolution of ligands by exponential enrichment. This method,
described primarily in 1990 [Ellington, AD, Szostak, JW, 1990. In vitro selection of RNA …

The use of nanotechnology in drug delivery and imaging in vivo is a rapidly expanding field.
The emphases of this review are on biophysical attributes of the drug delivery and imaging …

Rapid innovations in nanomedicine have increased the likelihood that engineered
nanomaterials will eventually come in contact with humans and the environment. The advent …

Agents able to bind tightly and selectively to disease markers can greatly benefit disease
diagnosis and therapy. Aptamers are functional molecules, usually DNA or RNA …

While pharmaceutical drugs have revolutionized human life, there are several features that
limit their full potential. This review draws attention to some of the obstacles currently facing …

Abstract Mucin 1 protein (MUC1) is a membrane-associated glycoprotein overexpressed in
the majority of human malignancies and considered as a predominant protein biomarker in …

Abstract Mucin 1 (MUC1) is a protein usually found on the apical surface of most normal
secretory epithelial cells. However, in most adenocarcinomas, MUC1 is overexpressed, so …