Long noncoding RNAs as biomarkers in cancer

L Bolha, M Ravnik-Glavač, D Glavač - Disease markers, 2017 - Wiley Online Library
Long noncoding RNAs (lncRNAs) are a relatively well‐characterized class of noncoding
RNA (ncRNA) molecules, involved in the regulation of various cell processes, including …

Biomarkers for prostate cancer: prostate-specific antigen and beyond

MJ Duffy - Clinical Chemistry and Laboratory Medicine (CCLM), 2020 - degruyter.com
In recent years, several new biomarkers supplementing the role of prostate-specific antigen
(PSA) have become available for men with prostate cancer. Although widely used in an ad …

Circulating long non-coding RNAs in cancer: current status and future perspectives

P Qi, X Zhou, X Du - Molecular cancer, 2016 - Springer
Long non-coding RNAs (lncRNAs) comprise a diverse class of RNA transcripts> 200
nucleotides in length with limited protein-coding potential. In addition to their possible role in …

Emerging biomarkers in the diagnosis of prostate cancer

X Filella, E Fernández-Galan… - Pharmacogenomics …, 2018 - Taylor & Francis
Prostate cancer (PCa) is the second most common cancer in men worldwide. A large
proportion of PCa are latent, never destined to progress or affect the patients' life. It is of …

Prostate cancer detection and prognosis: from prostate specific antigen (PSA) to exosomal biomarkers

X Filella, L Foj - International journal of molecular sciences, 2016 - mdpi.com
Prostate specific antigen (PSA) remains the most used biomarker in the management of
early prostate cancer (PCa), in spite of the problems related to false positive results and …

The clinical relevance of long non-coding RNAs in cancer

A Silva, M Bullock, G Calin - Cancers, 2015 - mdpi.com
Non-coding RNAs have long been associated with cancer development and progression,
and since their earliest discovery, their clinical potential in identifying and characterizing the …

Prediction medicine: biomarkers, risk calculators and magnetic resonance imaging as risk stratification tools in prostate cancer diagnosis

DF Osses, MJ Roobol, IG Schoots - International journal of molecular …, 2019 - mdpi.com
This review discusses the most recent evidence for currently available risk stratification tools
in the detection of clinically significant prostate cancer (csPCa), and evaluates diagnostic …

[HTML][HTML] The long non-coding RNA PCA3: an update of its functions and clinical applications as a biomarker in prostate cancer

AEG Lemos, A da Rocha Matos, LB Ferreira - Oncotarget, 2019 - ncbi.nlm.nih.gov
Abstract Prostate cancer antigen 3 (PCA3) is an overexpressed prostate long non-coding
RNA (lncRNA), transcribed from an intronic region at the long arm of human chromosome …

A novel long non-coding RNA linc-ZNF469-3 promotes lung metastasis through miR-574-5p-ZEB1 axis in triple negative breast cancer

PS Wang, CH Chou, CH Lin, YC Yao, HC Cheng, HY Li… - Oncogene, 2018 - nature.com
Triple-negative breast cancer (TNBC) patients usually lead to poor prognosis and survival
because of metastasis. The major sites for TNBC metastasis include the lungs, brain, liver …

Recent advances and future perspectives in the therapeutics of prostate cancer

GL Varaprasad, VK Gupta, K Prasad, E Kim… - … Hematology & Oncology, 2023 - Springer
Prostate cancer (PC) is one of the most common cancers in males and the fifth leading
reason of death. Age, ethnicity, family history, and genetic defects are major factors that …