Mitochondrial energetic adaptations encompass a plethora of conserved processes that
maintain cell and organismal fitness and survival in the changing environment by adjusting …

Peroxisomes are subcellular organelles that play a central role in human physiology by
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …

Mitophagy plays an important role in the maintenance of mitochondrial homeostasis and can
be categorized into two types: ubiquitin-mediated and receptor-mediated pathways. During …

Brown adipose tissue (BAT) displays the unique capacity to generate heat through
uncoupled oxidative phosphorylation that makes it a very attractive therapeutic target for …

As key organelles involved in cellular metabolism, mitochondria frequently undergo
adaptive changes in morphology, components and functions in response to various …

Autophagy is activated by prolonged fasting but cannot overcome the ensuing hepatic lipid
overload, resulting in fatty liver. Here, we describe a peroxisome-lysosome metabolic link …

Peroxisomes are involved in multiple metabolic processes, including fatty acid oxidation,
ether lipid synthesis, and reactive oxygen species (ROS) metabolism. Recent studies …

Dicarboxylic fatty acids are generated in the liver and kidney in a minor pathway called fatty
acid ω-oxidation. The effects of consuming dicarboxylic fatty acids as an alternative source …

The liver gene expression of the peroxisomal β-oxidation enzyme acyl-coenzyme A oxidase
1 (ACOX1), which catabolizes very long chain fatty acids (VLCFA), increases in the context …

To liberate fatty acids (FAs) from intracellular stores, lipolysis is regulated by the activity of
the lipases adipose triglyceride lipase (ATGL), hormone-sensitive lipase and …