The blood-brain barrier (BBB) prevents neurotoxic plasma components, blood cells, and
pathogens from entering the brain. At the same time, the BBB regulates transport of …

Cerebral small vessel disease (cSVD) has a crucial role in lacunar stroke and brain
hemorrhages and is a leading cause of cognitive decline and functional loss in elderly …

The modern antiretroviral treatment of human immunodeficiency virus (HIV-1) infection has
considerably lowered the incidence of opportunistic infections. With the exception of the …

Abstract Purpose of Review The purpose of this review was to examine characteristics that
may distinguish HIV-associated neurocognitive disorder (HAND) from early Alzheimer's …

Objectives: The objective of this study was to assess whether HIV-infected patients on long-
term successful combination antiretroviral therapy (cART) have more extensive white matter …

Human immunodeficiency virus (HIV) enters the brain soon after seroconversion and can
cause HIV-associated neurocognitive disorders (HAND). Although the more severe and …

Objective: HIV-associated neurocognitive disorders (HANDs) remain prevalent in patients
who receive HAART and may be associated with cumulative exposure to antiretroviral …

Objective: The spectrum of risk factors for HIV-associated cognitive impairment is likely very
broad and includes not only HIV/antiretroviral therapy-specific factors but also other …

Our aim was to examine the clinical relevance of white matter hyperintensities (WMH) in HIV.
We used an automated approach to quantify WMH volume in HIV seropositive (HIV+; n= 65) …

The growing number of people over age 50 with HIV requires research, policy, and practice
to develop a more comprehensive understanding of the health consequences of HIV in older …