Importance More than 42 000 Americans died of opioid overdoses in 2016, and the fatalities
continue to increase. This review analyzes the factors that triggered the opioid crisis and its …

The opioid crisis has grown to affect pregnant women and infants across the United States,
as evidenced by rising rates of opioid use disorder among pregnant women and neonatal …

Abstract Purpose of Review The opioid crisis most likely is the most profound public health
crisis our nation has faced. In 2015 alone, 52,000 people died of drug overdoses, with over …

Abstract The United States opioid epidemic is a nationwide public health crisis. Initially
driven by increased consumption and availability of pharmaceutical opioids, an increasing …

Objective: Neonatal abstinence syndrome (NAS), a postnatal opioid withdrawal syndrome,
increased threefold from 2000 to 2009. Since 2009, opioid pain reliever prescriptions and …

Prenatal substance use is a critical public health concern that is linked with several harmful
maternal and fetal consequences. The most frequently used substance in pregnancy is …

Background Pregnancy is a unique opportunity to provide broad and necessary medical
care for women-including treatment for Substance Use Disorders (SUD). The standard of …

Background The incidence of the neonatal abstinence syndrome, a drug-withdrawal
syndrome that most commonly occurs after in utero exposure to opioids, is known to have …

Background: Prescription opioid use during pregnancy has been associated with poor
outcomes for mothers and infants. Studies using administrative data have estimated that …

Neonatal abstinence syndrome (NAS) is a postnatal drug withdrawal syndrome in newborns
caused primarily by in utero exposure to opioids. In the United States, the incidence of NAS …