The prediction of drug–target binding and unbinding kinetics that occur on time scales
between milliseconds and several hours is a prime challenge for biased molecular …

Among the long-standing efforts to elucidate the physical mechanisms of protein–ligand
catch bonding, particular attention has been directed at the family of selectin proteins …

This article reviews the state of the art of the studies on charge regulation (CR) effects in
flexible weak polyelectrolytes (FWPE). The characteristic of FWPE is the strong coupling of …

Chitin is one of the most common polysaccharides and is abundant in the cell walls of fungi
and the shells of insects and aquatic organisms as a skeleton. The mechanism of how chitin …

Although frozen dough technology has demonstrated significant benefits, the mechanisms
underlying dough deterioration during freezing remain unclear. To overcome this obstacle …

Starch granule-surface proteins (SGSPs) and gluten proteins can interact to influence dough
quality. Despite their pronounced effects, the interaction mechanism remains insufficiently …

Mucins are the macromolecular key components of mucus. On wet epithelia of mammals,
mucin solutions and gels act as powerful biolubricants and reduce friction and wear by …

Protein–protein complexes can vary in mechanical stability depending on the direction from
which force is applied. Here, we investigated the mechanical stability of a complex between …

Chloroquine has been used as a potent antimalarial, anticancer drug, and prophylactic.
While chloroquine is known to interact with DNA, the details of DNA–ligand interactions …

Water-soluble arabinoxylans (AX) is an important dietary fiber in wheat bran that influence
the gluten network. However, a comprehensive understanding of the mechanism remains …