Cytochrome c (cyt c) is a small soluble heme protein characterized by a relatively flexible
structure, particularly in the ferric form, such that it is able to sample a broad conformational …

Since its discovery 75 years ago, a wealth of knowledge has accumulated on the role of
cardiolipin, the hallmark phospholipid of mitochondria, in bioenergetics and particularly on …

Programmed death (apoptosis) is turned on in damaged or unwanted cells to secure their
clean and safe self-elimination. The initial apoptotic events are coordinated in mitochondria …

Since the (re) discovery of cytochrome c (cyt c) in the early 1920s and subsequent detailed
characterization of its structure and function in mitochondrial electron transport, it took over …

Cytochrome c (cyt c) is a multifunctional protein with varying conformations. However, the
conformation of cyt c in its native environment, mitochondria, is still unclear. Here, we …

Cyt c (cytochrome c) has been traditionally envisioned as rapidly diffusing in two dimensions
at the surface of the mitochondrial inner membrane when not engaged in redox reactions …

The interaction of cytochrome c (cyt c) with mitochondrial mimetic vesicles of 1, 2-dipalmitoyl-
sn-glycero-3-phosphocholine, 1, 2-dipalmitoyl-sn-glycero-3-phosphoethanolamine, and …

We report a resonance Raman and UV–vis characterization of the active site structure of
oxidatively modified forms of cytochrome c (Cyt-c) free in solution and in complexes with …

The increased production of NO during the early stages of apoptosis indicates its potential
involvement in the regulation of programmed cell death through yet to be identified …

Oxidation of cardiolipin (CL) by its complex with cytochrome c (cyt c) plays a crucial role in
triggering apoptosis. Through a combination of magnetic circular dichroism spectroscopy …