Advancing Yarrowia lipolytica as a superior biomanufacturing platform by tuning gene expression using promoter engineering
ML Sun, TQ Shi, L Lin, R Ledesma-Amaro, XJ Ji - Bioresource Technology, 2022 - Elsevier
Yarrowia lipolytica is recognized as an excellent non-conventional yeast in the field of
biomanufacturing, where it is used as a host to produce oleochemicals, terpenes, organic …
biomanufacturing, where it is used as a host to produce oleochemicals, terpenes, organic …
Plant promoters: an approach of structure and function
MS Porto, MPN Pinheiro, VGL Batista… - Molecular …, 2014 - Springer
With current advances in genomics, several technological processes have been generated,
resulting in improvement in different segments of molecular research involving prokaryotic …
resulting in improvement in different segments of molecular research involving prokaryotic …
Single-molecule visualization of twin-supercoiled domains generated during transcription
R Janissen, R Barth, M Polinder… - Nucleic acids …, 2024 - academic.oup.com
Transcription-coupled supercoiling of DNA is a key factor in chromosome compaction and
the regulation of genetic processes in all domains of life. It has become common knowledge …
the regulation of genetic processes in all domains of life. It has become common knowledge …
Blue light-mediated transcriptional activation and repression of gene expression in bacteria
P Jayaraman, K Devarajan, TK Chua… - Nucleic acids …, 2016 - academic.oup.com
Light-regulated modules offer unprecedented new ways to control cellular behavior in
precise spatial and temporal resolution. The availability of such tools may dramatically …
precise spatial and temporal resolution. The availability of such tools may dramatically …
MethSMRT: an integrative database for DNA N6-methyladenine and N4-methylcytosine generated by single-molecular real-time sequencing
P Ye, Y Luan, K Chen, Y Liu, C **ao… - Nucleic acids …, 2016 - academic.oup.com
DNA methylation is an important type of epigenetic modifications, where 5-methylcytosine
(5mC), 6-methyadenine (6mA) and 4-methylcytosine (4mC) are the most common types …
(5mC), 6-methyadenine (6mA) and 4-methylcytosine (4mC) are the most common types …
Recent advances in the applications of promoter engineering for the optimization of metabolite biosynthesis
Cell metabolism in living organisms is largely regulated at the transcriptional level, and the
promoters are regarded as basic regulatory elements responsible for transcription initiation …
promoters are regarded as basic regulatory elements responsible for transcription initiation …
Tailored UPRE2 variants for dynamic gene regulation in yeast
C **ao, X Liu, Y Pan, Y Li, L Qin… - Proceedings of the …, 2024 - National Acad Sciences
Genetic elements are foundational in synthetic biology serving as vital building blocks. They
enable programming host cells for efficient production of valuable chemicals and …
enable programming host cells for efficient production of valuable chemicals and …
Generic eukaryotic core promoter prediction using structural features of DNA
Despite many recent efforts, in silico identification of promoter regions is still in its infancy.
However, the accurate identification and delineation of promoter regions is important for …
However, the accurate identification and delineation of promoter regions is important for …
Diversity, expansion, and evolutionary novelty of plant DNA-binding transcription factor families
Plant transcription factors (TFs) that interact with specific sequences via DNA-binding
domains are crucial for regulating transcriptional initiation and are fundamental to plant …
domains are crucial for regulating transcriptional initiation and are fundamental to plant …
Towards a molecular dynamics consensus view of B-DNA flexibility
We present a systematic study of B-DNA flexibility in aqueous solution using long-scale
molecular dynamics simulations with the two more recent versions of nucleic acids force …
molecular dynamics simulations with the two more recent versions of nucleic acids force …