MHC genotypes associate with resistance to a frog-killing fungus
The emerging amphibian disease chytridiomycosis is caused by the fungal pathogen
Batrachochytrium dendrobatidis (Bd). Amphibian populations and species differ in …
Batrachochytrium dendrobatidis (Bd). Amphibian populations and species differ in …
Adaptive tolerance to a pathogenic fungus drives major histocompatibility complex evolution in natural amphibian populations
Amphibians have been affected globally by the disease chytridiomycosis, caused by the
fungus Batrachochytrium dendrobatidis (Bd), and we are just now beginning to understand …
fungus Batrachochytrium dendrobatidis (Bd), and we are just now beginning to understand …
Susceptibility of amphibians to chytridiomycosis is associated with MHC class II conformation
The pathogenic chytrid fungus Batrachochytrium dendrobatidis (Bd) can cause precipitous
population declines in its amphibian hosts. Responses of individuals to infection vary greatly …
population declines in its amphibian hosts. Responses of individuals to infection vary greatly …
Sustained immune activation is associated with susceptibility to the amphibian chytrid fungus
The disease chytridiomycosis caused by the fungus Bd has devastated amphibian
populations worldwide. Functional genomic contributions to host susceptibility remain …
populations worldwide. Functional genomic contributions to host susceptibility remain …
Interspecific hybridization increases MHC class II diversity in two sister species of newts
Our understanding of the evolutionary mechanisms generating variation within the highly
polymorphic major histocompatibility complex (MHC) genes remains incomplete. Assessing …
polymorphic major histocompatibility complex (MHC) genes remains incomplete. Assessing …
Spatiotemporal adaptive evolution of an MHC immune gene in a frog-fungus disease system
Genetic diversity of major histocompatibility complex (MHC) genes is linked to reduced
pathogen susceptibility in amphibians, but few studies also examine broad spatial and …
pathogen susceptibility in amphibians, but few studies also examine broad spatial and …
The Amphibian Major Histocompatibility Complex—A Review and Future Outlook
The major histocompatibility complex (MHC) is a cluster of functionally related genes
encoding proteins which, among other functions, mediate immune system activation. While …
encoding proteins which, among other functions, mediate immune system activation. While …
Lost but not forgotten: MHC genotypes predict overwinter survival despite depauperate MHC diversity in a declining frog
The amphibian disease chytridiomycosis, caused by the fungus Batrachochytrium
dendrobatidis (Bd), has contributed to the decline of Chiricahua leopard frogs (Rana …
dendrobatidis (Bd), has contributed to the decline of Chiricahua leopard frogs (Rana …
Invasive bullfrogs maintain MHC polymorphism including alleles associated with chytrid fungal infection
Maintenance of genetic diversity at adaptive loci may facilitate invasions by non-native
species by allowing populations to adapt to novel environments, despite the loss of diversity …
species by allowing populations to adapt to novel environments, despite the loss of diversity …
Functional variation at an expressed MHC class IIβ locus associates with Ranavirus infection intensity in larval anuran populations
Infectious diseases are causing catastrophic losses to global biodiversity. Iridoviruses in the
genus Ranavirus are among the leading causes of amphibian disease-related mortality …
genus Ranavirus are among the leading causes of amphibian disease-related mortality …