The use of next generation sequencing for improving food safety: Translation into practice

B Jagadeesan, P Gerner-Smidt, MW Allard, S Leuillet… - Food …, 2019 - Elsevier
Abstract Next Generation Sequencing (NGS) combined with powerful bioinformatic
approaches are revolutionising food microbiology. Whole genome sequencing (WGS) of …

Sequencing and beyond: integrating molecular'omics' for microbial community profiling

EA Franzosa, T Hsu, A Sirota-Madi… - Nature Reviews …, 2015 - nature.com
High-throughput DNA sequencing has proven invaluable for investigating diverse
environmental and host-associated microbial communities. In this Review, we discuss …

Introducing the bacterial and viral bioinformatics resource center (BV-BRC): a resource combining PATRIC, IRD and ViPR

RD Olson, R Assaf, T Brettin, N Conrad… - Nucleic acids …, 2023 - academic.oup.com
Abstract The National Institute of Allergy and Infectious Diseases (NIAID) established the
Bioinformatics Resource Center (BRC) program to assist researchers with analyzing the …

Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine

A Heinken, J Hertel, G Acharya, DA Ravcheev… - Nature …, 2023 - nature.com
The human microbiome influences the efficacy and safety of a wide variety of commonly
prescribed drugs. Designing precision medicine approaches that incorporate microbial …

The PATRIC Bioinformatics Resource Center: expanding data and analysis capabilities

JJ Davis, AR Wattam, RK Aziz, T Brettin… - Nucleic acids …, 2020 - academic.oup.com
Abstract The PathoSystems Resource Integration Center (PATRIC) is the bacterial
Bioinformatics Resource Center funded by the National Institute of Allergy and Infectious …

Bifidobacterium infantis treatment promotes weight gain in Bangladeshi infants with severe acute malnutrition

MJ Barratt, S Nuzhat, K Ahsan, SA Frese… - Science Translational …, 2022 - science.org
Disrupted development of the gut microbiota is a contributing cause of childhood
malnutrition. Bifidobacterium longum subspecies infantis is a prominent early colonizer of …

Improvements to PATRIC, the all-bacterial bioinformatics database and analysis resource center

AR Wattam, JJ Davis, R Assaf, S Boisvert… - Nucleic acids …, 2017 - academic.oup.com
Abstract The Pathosystems Resource Integration Center (PATRIC) is the bacterial
Bioinformatics Resource Center (https://www. patricbrc. org). Recent changes to PATRIC …

Gut microbial metabolite TMAO enhances platelet hyperreactivity and thrombosis risk

W Zhu, JC Gregory, E Org, JA Buffa, N Gupta, Z Wang… - Cell, 2016 - cell.com
Normal platelet function is critical to blood hemostasis and maintenance of a closed
circulatory system. Heightened platelet reactivity, however, is associated with …

Effects of microbiota-directed foods in gnotobiotic animals and undernourished children

JL Gehrig, S Venkatesh, HW Chang, MC Hibberd… - Science, 2019 - science.org
INTRODUCTION There is a dimension to postnatal human development that involves
assembly of microbial communities in different body habitats, including the gut. Children with …

Generation of genome-scale metabolic reconstructions for 773 members of the human gut microbiota

S Magnúsdóttir, A Heinken, L Kutt, DA Ravcheev… - Nature …, 2017 - nature.com
Genome-scale metabolic models derived from human gut metagenomic data can be used
as a framework to elucidate how microbial communities modulate human metabolism and …