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A review on diverse heterocyclic compounds as the privileged scaffolds in antimalarial drug discovery
The upward extend of malaria collectively with the emergence of resistance against
predictable drugs has put enormous pressure on public health systems to introduce new …
predictable drugs has put enormous pressure on public health systems to introduce new …
1, 3, 5‐Triazine: A versatile pharmacophore with diverse biological activities
S Singh, MK Mandal, A Masih, A Saha… - Archiv der …, 2021 - Wiley Online Library
Triazine and its derivatives have been the epicenter of chemotherapeutic molecules due to
their effective biological activities, such as antibacterial, fungicidal, antimalarial, anticancer …
their effective biological activities, such as antibacterial, fungicidal, antimalarial, anticancer …
“Recycling” classical drugs for malaria
Malaria has been a human health concern ever since the dawn of mankind, but despite the
huge struggles made to date to fight this infection, in 2012 over half a million people were …
huge struggles made to date to fight this infection, in 2012 over half a million people were …
Functionalized triazines and tetrazines: Synthesis and applications
The molecules possessing triazine and tetrazine moieties belong to a special class of
heterocyclic compounds. Both triazines and tetrazines are building blocks and have …
heterocyclic compounds. Both triazines and tetrazines are building blocks and have …
Design and discovery of novel monastrol-1,3,5-triazines as potent anti-breast cancer agent via attenuating Epidermal Growth Factor Receptor tyrosine kinase
A novel series of hybrid analogues of monastrol-1, 3, 5-triazine were designed and
developed via one-pot synthesis using Bi (NO3) 3 as a catalyst. Entire compounds were …
developed via one-pot synthesis using Bi (NO3) 3 as a catalyst. Entire compounds were …
Quinine conjugates and quinine analogues as potential antimalarial agents
RA Jones, SS Panda, CD Hall - European journal of medicinal chemistry, 2015 - Elsevier
Malaria is a tropical disease, prevalent in Southeast Asia and Africa, resulting in over half a
million deaths annually; efforts to develop new antimalarial agents are therefore particularly …
million deaths annually; efforts to develop new antimalarial agents are therefore particularly …
Hybrid molecules with potential in vitro antiplasmodial and in vivo antimalarial activity against drug‐resistant Plasmodium falciparum
LS Feng, Z Xu, L Chang, C Li, XF Yan… - Medicinal Research …, 2020 - Wiley Online Library
Malaria is a tropical disease, leading to around half a million deaths annually. Antimalarials
such as quinolines are crucial to fight against malaria, but malaria control is extremely …
such as quinolines are crucial to fight against malaria, but malaria control is extremely …
Privileged S-Triazines: Structure and Pharmacological Applications
DR Shah, RP Modh, KH Chikhalia - Future medicinal chemistry, 2014 - Taylor & Francis
This review summarizes recent reports on s-triazine and its respective analogs from the
medicinal chemistry angle. Due to its high reactivity and binding characteristic towards …
medicinal chemistry angle. Due to its high reactivity and binding characteristic towards …
Design, synthesis, anticancer, antibacterial, and antifungal evaluation of 4‐aminoquinoline‐1, 3, 5‐triazine derivatives
Abstract A series of 4‐aminoquinoline 1, 3, 5‐triazine derivatives were synthesized and
evaluated for anticancer activity against cancer cell lines HeLa, MCF‐7, HL‐60, HepG2 …
evaluated for anticancer activity against cancer cell lines HeLa, MCF‐7, HL‐60, HepG2 …
A review of antimalarial activity of two or three nitrogen atoms containing heterocyclic compounds
Malaria, a nocuous disease, which has become a major challenge for the health resulting in
deaths of millions of people around the globe. Malaria is a parasitic disease propagated by …
deaths of millions of people around the globe. Malaria is a parasitic disease propagated by …