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Tutorial: a guide to performing polygenic risk score analyses
A polygenic score (PGS) or polygenic risk score (PRS) is an estimate of an individual's
genetic liability to a trait or disease, calculated according to their genotype profile and …
genetic liability to a trait or disease, calculated according to their genotype profile and …
The new genetics of intelligence
Intelligence—the ability to learn, reason and solve problems—is at the forefront of
behavioural genetic research. Intelligence is highly heritable and predicts important …
behavioural genetic research. Intelligence is highly heritable and predicts important …
PRSice-2: Polygenic Risk Score software for biobank-scale data
Background Polygenic risk score (PRS) analyses have become an integral part of
biomedical research, exploited to gain insights into shared aetiology among traits, to control …
biomedical research, exploited to gain insights into shared aetiology among traits, to control …
Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence
Intelligence is associated with important economic and health-related life outcomes 1.
Despite intelligence having substantial heritability 2 (0.54) and a confirmed polygenic …
Despite intelligence having substantial heritability 2 (0.54) and a confirmed polygenic …
[HTML][HTML] Comparing within-and between-family polygenic score prediction
Polygenic scores are a popular tool for prediction of complex traits. However, prediction
estimates in samples of unrelated participants can include effects of population stratification …
estimates in samples of unrelated participants can include effects of population stratification …
[КНИГА][B] Concepts and theories of human development
RM Lerner - 2018 - taylorfrancis.com
Concepts and Theories of Human Development is the most comprehensive and in-depth
overview of the foundational theoretical contributions to understanding human development …
overview of the foundational theoretical contributions to understanding human development …
Multi-polygenic score approach to trait prediction
A primary goal of polygenic scores, which aggregate the effects of thousands of trait-
associated DNA variants discovered in genome-wide association studies (GWASs), is to …
associated DNA variants discovered in genome-wide association studies (GWASs), is to …
A polygenic p factor for major psychiatric disorders
It has recently been proposed that a single dimension, called the p factor, can capture a
person's liability to mental disorder. Relevant to the p hypothesis, recent genetic research …
person's liability to mental disorder. Relevant to the p hypothesis, recent genetic research …
Twins early development study: A genetically sensitive investigation into behavioral and cognitive development from infancy to emerging adulthood
The Twins Early Development Study (TEDS) is a longitudinal twin study that recruited over
16,000 twin-pairs born between 1994 and 1996 in England and Wales through national birth …
16,000 twin-pairs born between 1994 and 1996 in England and Wales through national birth …
New literacy challenge for the twenty-first century: genetic knowledge is poor even among well educated
We live in an age of rapidly advancing genetic research. This research is generating new
knowledge that has implications for personal health and well-being. The present study …
knowledge that has implications for personal health and well-being. The present study …